Articles:

P. N. Palma, M. J. Bonifácio, A. I. Loureiro, L. C. Wright, D. A. Learmonth, and P. Soares-da-Silva

Molecular Modeling and Metabolic Studies of The Interaction of Catechol-O-Methyltransferase and a New Nitrocatechol Inhibitor
Drug Metab Dispos 2003 31: 250-258. [Abstract] [Full Text] [PDF]  

Lizette Granberg, Anna Östergren, Ingvar Brandt, and Eva B. Brittebo

CYP1A1 and CYP1B1 in Blood-Brain Interfaces: CYP1A1-Dependent Bioactivation of 7,12-Dimethylbenz(a)anthracene in Endothelial Cells
Drug Metab Dispos 2003 31: 259-265. [Abstract] [Full Text] [PDF]  

Simonetta Gemma, Luciano Vittozzi, and Emanuela Testai

Metabolism of Chloroform in the Human Liver and Identification of the Competent P450s
Drug Metab Dispos 2003 31: 266-274. [Abstract] [Full Text] [PDF]  

J. M. Tréluyer, G. Bowers, N. Cazali, M. Sonnier, E. Rey, G. Pons, and T. Cresteil

Oxidative Metabolism of Amprenavir in the Human Liver. Effect of the CYP3A Maturation
Drug Metab Dispos 2003 31: 275-281. [Abstract] [Full Text] [PDF]  

Robert J. Edwards, Roger J. Price, Patricia S. Watts, Anthony B. Renwick, J. Michael Tredger, Alan R. Boobis, and Brian G. Lake

Induction of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
Drug Metab Dispos 2003 31: 282-288. [Abstract] [Full Text] [PDF]  

Kirk M. Bertelsen, Karthik Venkatakrishnan, Lisa L. von Moltke, R. Scott Obach, and David J. Greenblatt

Apparent Mechanism-based Inhibition of Human CYP2D6 in Vitro by Paroxetine: Comparison with Fluoxetine and Quinidine
Drug Metab Dispos 2003 31: 289-293. [Abstract] [Full Text] [PDF]  

Ulf G. Eriksson, Ulf Bredberg, Kurt-Jürgen Hoffmann, Anneli Thuresson, Margareth Gabrielsson, Hans Ericsson, Martin Ahnoff, Kristina Gislén, Gunnar Fager, and David Gustafsson

Absorption, Distribution, Metabolism, and Excretion of Ximelagatran, an Oral Direct Thrombin Inhibitor, in Rats, Dogs, and Humans
Drug Metab Dispos 2003 31: 294-305. [Abstract] [Full Text] [PDF]  

Poh-Gek Forkert, Lawrence Lash, Robert Tardif, Nongnuj Tanphaichitr, Catherine Vandevoort, and Madeleine Moussa

Identification of Trichloroethylene and Its Metabolites in Human Seminal Fluid of Workers Exposed to Trichloroethylene
Drug Metab Dispos 2003 31: 306-311. [Abstract] [Full Text] [PDF]  

Cuiping Chen, Elizabeth Hanson, John W. Watson, and Jae S. Lee

P-Glycoprotein Limits the Brain Penetration of Nonsedating but not Sedating H1-Antagonists
Drug Metab Dispos 2003 31: 312-318. [Abstract] [Full Text] [PDF]  

Frédéric Imbert, Méryam Jardin, Christine Fernandez, Jean Charles Gantier, Françoise Dromer, Gabriel Baron, France Mentre, Ludy van Beijsterveldt, Eric Singlas, and François Gimenez

Effect of Efflux Inhibition on Brain Uptake of Itraconazole in Mice Infected with Cryptococcus neoformans
Drug Metab Dispos 2003 31: 319-325. [Abstract] [Full Text] [PDF]  

M. K. Shelby, N. J. Cherrington, N. R. Vansell, and C. D. Klaassen

Tissue mRNA Expression of the Rat UDP-Glucuronosyltransferase Gene Family
Drug Metab Dispos 2003 31: 326-333. [Abstract] [Full Text] [PDF]  

Minxia M. He, Trent L. Abraham, Thomas J. Lindsay, Hans C. Schaefer, Isabelle J. Pouliquen, Chris Payne, Boris Czeskis, Lisa A. Shipley, Stuart D. Oliver, and Malcolm I. Mitchell

Metabolism and Disposition of the Antihypertensive Agent Moxonidine in Humans
Drug Metab Dispos 2003 31: 334-342. [Abstract] [Full Text] [PDF]  

Short Communications:

Amit S. Kalgutkar, Timothy J. Taylor, Karthik Venkatakrishnan, and Emre M. Isin

Assessment of the Contributions of CYP3A4 and CYP3A5 in the Metabolism of the Antipsychotic Agent Haloperidol to Its Potentially Neurotoxic Pyridinium Metabolite and Effect of Antidepressants on the Bioactivation Pathway
Drug Metab Dispos 2003 31: 243-249. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Robert L. Walsky and R. Scott Obach

Verification of the Selectivity of (+)N-3-Benzylnirvanol as a CYP2C19 Inhibitor
Drug Metab Dispos 2003 31: 343. [Full Text] [PDF]  

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