Articles:

Chitra Sridar, Theunis C. Goosen, Ute M. Kent, J. Andrew Williams, and Paul F. Hollenberg

SILYBIN INACTIVATES CYTOCHROMES P450 3A4 AND 2C9 AND INHIBITS MAJOR HEPATIC GLUCURONOSYLTRANSFERASES
Drug Metab Dispos 2004 32: 587-594. [Abstract] [Full Text] [PDF]  

Virginia H. Black and Linda C. Quattrochi

MOLECULAR CLONING OF THE GUINEA PIG CYP1A2 GENE 5'-FLANKING REGION: IDENTIFICATION OF FUNCTIONAL AROMATIC HYDROCARBON RESPONSE ELEMENT AND CHARACTERIZATION OF CYP1A2 EXPRESSION IN GPC16 CELLS
Drug Metab Dispos 2004 32: 595-602. [Abstract] [Full Text] [PDF]  

Keith W. Ward and Brian R. Smith

A COMPREHENSIVE QUANTITATIVE AND QUALITATIVE EVALUATION OF EXTRAPOLATION OF INTRAVENOUS PHARMACOKINETIC PARAMETERS FROM RAT, DOG, AND MONKEY TO HUMANS. I. CLEARANCE
Drug Metab Dispos 2004 32: 603-611. [Abstract] [Full Text] [PDF] Appendix  

Keith W. Ward and Brian R. Smith

A COMPREHENSIVE QUANTITATIVE AND QUALITATIVE EVALUATION OF EXTRAPOLATION OF INTRAVENOUS PHARMACOKINETIC PARAMETERS FROM RAT, DOG, AND MONKEY TO HUMANS. II. VOLUME OF DISTRIBUTION AND MEAN RESIDENCE TIME
Drug Metab Dispos 2004 32: 612-619. [Abstract] [Full Text] [PDF]  

Susan C. N. Buist and Curtis D. Klaassen

RAT AND MOUSE DIFFERENCES IN GENDER-PREDOMINANT EXPRESSION OF ORGANIC ANION TRANSPORTER (OAT1–3; SLC22A6–8) mRNA LEVELS
Drug Metab Dispos 2004 32: 620-625. [Abstract] [Full Text] [PDF]  

Miia Turpeinen, Riina Nieminen, Tarja Juntunen, Päivi Taavitsainen, Hannu Raunio, and Olavi Pelkonen

SELECTIVE INHIBITION OF CYP2B6-CATALYZED BUPROPION HYDROXYLATION IN HUMAN LIVER MICROSOMES IN VITRO
Drug Metab Dispos 2004 32: 626-631. [Abstract] [Full Text] [PDF]  

Mark J. Anderton, Margaret M. Manson, Richard Verschoyle, Andreas Gescher, William P. Steward, Marion L. Williams, and Donald E. Mager

PHYSIOLOGICAL MODELING OF FORMULATED AND CRYSTALLINE 3,3'-DIINDOLYLMETHANE PHARMACOKINETICS FOLLOWING ORAL ADMINISTRATION IN MICE
Drug Metab Dispos 2004 32: 632-638. [Abstract] [Full Text] [PDF]  

Kan He, Rasmy E. Talaat, William F. Pool, Michael D. Reily, Jessica E. Reed, Alexander J. Bridges, and Thomas F. Woolf

METABOLIC ACTIVATION OF TROGLITAZONE: IDENTIFICATION OF A REACTIVE METABOLITE AND MECHANISMS INVOLVED
Drug Metab Dispos 2004 32: 639-646. [Abstract] [Full Text] [PDF]  

Robert L. Walsky and R. Scott Obach

VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES
Drug Metab Dispos 2004 32: 647-660. [Abstract] [Full Text] [PDF]  

H. Frederiksen and H. Frandsen

IDENTIFICATION OF METABOLITES IN URINE AND FECES FROM RATS DOSED WITH THE HETEROCYCLIC AMINE, 2-AMINO-3-METHYL-9H-PYRIDO[2,3-b]INDOLE (MeAC)
Drug Metab Dispos 2004 32: 661-665. [Abstract] [Full Text] [PDF]  

Radka Vaclavikova, Pavel Soucek, Lenka Svobodova, Pavel Anzenbacher, Petr Simek, F. Peter Guengerich, and Ivan Gut

DIFFERENT IN VITRO METABOLISM OF PACLITAXEL AND DOCETAXEL IN HUMANS, RATS, PIGS, AND MINIPIGS
Drug Metab Dispos 2004 32: 666-674. [Abstract] [Full Text] [PDF]  

Jürgen Borlak, Ingo Schulte, and Thomas Thum

ANDROGEN METABOLISM IN THYMUS OF FETAL AND ADULT RATS
Drug Metab Dispos 2004 32: 675-679. [Abstract] [Full Text] [PDF]  

Short Communications:

Muneaki Hidaka, Ken-ichi Fujita, Tetsuya Ogikubo, Keishi Yamasaki, Tomomi Iwakiri, Manabu Okumura, Hirofumi Kodama, and Kazuhiko Arimori

POTENT INHIBITION BY STAR FRUIT OF HUMAN CYTOCHROME P450 3A (CYP3A) ACTIVITY
Drug Metab Dispos 2004 32: 581-583. [Abstract] [Full Text] [PDF]  

Xiaoxin Cai, Regina W. Wang, Richard W. Edom, David C. Evans, Magang Shou, A. David Rodrigues, Wensheng Liu, Dennis C. Dean, and Thomas A. Baillie

VALIDATION OF (-)-N-3-BENZYL-PHENOBARBITAL AS A SELECTIVE INHIBITOR OF CYP2C19 IN HUMAN LIVER MICROSOMES
Drug Metab Dispos 2004 32: 584-586. [Abstract] [Full Text] [PDF]  

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