Articles:

Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh, Ayano Kanoh, Osamu Tamura, Hiroyuki Ishibashi, and Tsuyoshi Yokoi

TRANS-3'-HYDROXYCOTININE O- AND N-GLUCURONIDATIONS IN HUMAN LIVER MICROSOMES
Drug Metab Dispos 2005 33: 23-30. Published online October 6, 2004; 10.1124/dmd.104.001701 [Abstract] [Full Text] [PDF]  

Markus Grube, Henriette Meyer zu Schwabedissen, Katrin Draber, Damaris Präger, Klaus-Uwe Möritz, Knud Linnemann, Christoph Fusch, Gabriele Jedlitschky, and Heyo K. Kroemer

EXPRESSION, LOCALIZATION, AND FUNCTION OF THE CARNITINE TRANSPORTER OCTN2 (SLC22A5) IN HUMAN PLACENTA
Drug Metab Dispos 2005 33: 31-37. Published online October 14, 2004; 10.1124/dmd.104.001560 [Abstract] [Full Text] [PDF]  

Mei-Fei Yueh, Marleen Kawahara, and Judy Raucy

HIGH VOLUME BIOASSAYS TO ASSESS CYP3A4-MEDIATED DRUG INTERACTIONS: INDUCTION AND INHIBITION IN A SINGLE CELL LINE
Drug Metab Dispos 2005 33: 38-48. Published online October 1, 2004; 10.1124/dmd.104.001594 [Abstract] [Full Text] [PDF]  

Angéline Gradolatto, Jean-Philippe Basly, Raymond Berges, Caroline Teyssier, Marie-Christine Chagnon, Marie-Héléne Siess, and Marie-Chantal Canivenc-Lavier

PHARMACOKINETICS AND METABOLISM OF APIGENIN IN FEMALE AND MALE RATS AFTER A SINGLE ORAL ADMINISTRATION
Drug Metab Dispos 2005 33: 49-54. Published online October 4, 2004; 10.1124/dmd.104.000893 [Abstract] [Full Text] [PDF]  

Hiroki Inoue, Akio Tsuruta, Satoko Kudo, Takako Ishii, Yusuke Fukushima, Hidetomo Iwano, Hiroshi Yokota, and Seiyu Kato

BISPHENOL A GLUCURONIDATION AND EXCRETION IN LIVER OF PREGNANT AND NONPREGNANT FEMALE RATS
Drug Metab Dispos 2005 33: 55-59. Published online October 4, 2004; 10.1124/dmd.104.001537 [Abstract] [Full Text] [PDF]  

Hidefumi Kaji and Toshiyuki Kume

CHARACTERIZATION OF AFLOQUALONE N-GLUCURONIDATION: SPECIES DIFFERENCES AND IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ISOFORM(S)
Drug Metab Dispos 2005 33: 60-67. Published online October 8, 2004; 10.1124/dmd.104.001925 [Abstract] [Full Text] [PDF]  

Marianne Garland, Kirsten M. Abildskov, Tung-wah Kiu, Salha S. Daniel, and Raymond I. Stark

THE CONTRIBUTION OF FETAL METABOLISM TO THE DISPOSITION OF MORPHINE
Drug Metab Dispos 2005 33: 68-76. Published online October 19, 2004; 10.1124/dmd.104.001388 [Abstract] [Full Text] [PDF]  

Laura J. Webb, Kristini K. Miles, Diana J. Auyeung, Fay K. Kessler, and Joseph K. Ritter

ANALYSIS OF SUBSTRATE SPECIFICITIES AND TISSUE EXPRESSION OF RAT UDP-GLUCURONOSYLTRANSFERASES UGT1A7 AND UGT1A8
Drug Metab Dispos 2005 33: 77-82. Published online October 22, 2004; 10.1124/dmd.104.001321 [Abstract] [Full Text] [PDF]  

Donglu Zhang, Rajesh Krishna, Lifei Wang, Jianing Zeng, James Mitroka, Renke Dai, Narayanan Narasimhan, Richard A. Reeves, Nuggehally R. Srinivas, and Lewis J. Klunk

METABOLISM, PHARMACOKINETICS, AND PROTEIN COVALENT BINDING OF RADIOLABELED MAXIPOST (BMS-204352) IN HUMANS
Drug Metab Dispos 2005 33: 83-93. Published online October 22, 2004; 10.1124/dmd.104.001412 [Abstract] [Full Text] [PDF]  

Daisuke Kobayashi, Ichiro Ieiri, Takeshi Hirota, Hiroshi Takane, Shinji Maegawa, Junzo Kigawa, Hiroshi Suzuki, Eiji Nanba, Mitsuo Oshimura, Naoki Terakawa, Kenji Otsubo, Kazunori Mine, and Yuichi Sugiyama

FUNCTIONAL ASSESSMENT OF ABCG2 (BCRP) GENE POLYMORPHISMS TO PROTEIN EXPRESSION IN HUMAN PLACENTA
Drug Metab Dispos 2005 33: 94-101. Published online October 8, 2004; 10.1124/dmd.104.001628 [Abstract] [Full Text] [PDF]  

Noriyuki Kasai, Toshiyuki Sakaki, Raku Shinkyo, Shin-ichi Ikushiro, Takashi Iyanagi, Miho Ohta, and Kuniyo Inouye

METABOLISM OF 26,26,26,27,27,27-F₆-1,23S,25-TRIHYDROXYVITAMIN D₃ BY HUMAN UDP-GLUCURONOSYLTRANSFERASE 1A3^*
Drug Metab Dispos 2005 33: 102-107. Published online October 26, 2004; 10.1124/dmd.104.002303 [Abstract] [Full Text] [PDF]  

M. Teresa Donato, Alfonso Serralta, Nuria Jiménez, Gabriela Pérez, José V. Castell, José Mir, and M. José Gómez-Lechón

LIVER GRAFTS PRESERVED IN CELSIOR SOLUTION AS SOURCE OF HEPATOCYTES FOR DRUG METABOLISM STUDIES: COMPARISON WITH SURGICAL LIVER BIOPSIES
Drug Metab Dispos 2005 33: 108-114. Published online September 24, 2004; 10.1124/dmd.104.001545 [Abstract] [Full Text] [PDF]  

Sarah J. Griffin and J. Brian Houston

PREDICTION OF IN VITRO INTRINSIC CLEARANCE FROM HEPATOCYTES: COMPARISON OF SUSPENSIONS AND MONOLAYER CULTURES
Drug Metab Dispos 2005 33: 115-120. [Abstract] [Full Text] [PDF]  

Shiyao Xu, Bing Zhu, Yohannes Teffera, Deborah E. Pan, Charles G. Caldwell, George Doss, Ralph A. Stearns, David C. Evans, and Maria G. Beconi

METABOLIC ACTIVATION OF FLUOROPYRROLIDINE DIPEPTIDYL PEPTIDASE-IV INHIBITORS BY RAT LIVER MICROSOMES
Drug Metab Dispos 2005 33: 121-130. Published online October 14, 2004; 10.1124/dmd.104.001842 [Abstract] [Full Text] [PDF]  

Ezra R. Lowe, Andrew C. Everett, Anthony J. Lee, Miranda Lau, Anwar Y. Dunbar, Vladimir Berka, Ah-lim Tsai, and Yoichi Osawa

TIME-DEPENDENT INHIBITION AND TETRAHYDROBIOPTERIN DEPLETION OF ENDOTHELIAL NITRIC-OXIDE SYNTHASE CAUSED BY CIGARETTES
Drug Metab Dispos 2005 33: 131-138. Published online October 6, 2004; 10.1124/dmd.104.001891 [Abstract] [Full Text] [PDF]  

Nicolas Picard, Damrong Ratanasavanh, Aurélie Prémaud, Yonnick Le Meur, and Pierre Marquet

IDENTIFICATION OF THE UDP-GLUCURONOSYLTRANSFERASE ISOFORMS INVOLVED IN MYCOPHENOLIC ACID PHASE II METABOLISM
Drug Metab Dispos 2005 33: 139-146. Published online October 6, 2004; 10.1124/dmd.104.001651 [Abstract] [Full Text] [PDF]  

Hai-Lin Fang, Masumeh Abdolalipour, Zhengbo Duanmu, Jeffrey R. Smigelski, Amy Weckle, Thomas A. Kocarek, and Melissa Runge-Morris

REGULATION OF GLUCOCORTICOID-INDUCIBLE HYDROXYSTEROID SULFOTRANSFERASE (SULT2A-40/41) GENE TRANSCRIPTION IN PRIMARY CULTURED RAT HEPATOCYTES: ROLE OF CCAAT/ENHANCER-BINDING PROTEIN LIVER-ENRICHED TRANSCRIPTION FACTORS
Drug Metab Dispos 2005 33: 147-156. Published online October 22, 2004; 10.1124/dmd.104.000281 [Abstract] [Full Text] [PDF]  

Eszter Hazai and David Kupfer

INTERACTIONS BETWEEN CYP2C9 AND CYP2C19 IN RECONSTITUTED BINARY SYSTEMS INFLUENCE THEIR CATALYTIC ACTIVITY: POSSIBLE RATIONALE FOR THE INABILITY OF CYP2C19 TO CATALYZE METHOXYCHLOR DEMETHYLATION IN HUMAN LIVER MICROSOMES
Drug Metab Dispos 2005 33: 157-164. Published online October 14, 2004; 10.1124/dmd.104.001578 [Abstract] [Full Text] [PDF]  

Angela Doran, R. Scott Obach, Bill J. Smith, Natilie A. Hosea, Stacey Becker, Ernesto Callegari, Cuiping Chen, Xi Chen, Edna Choo, Julie Cianfrogna, Loretta M. Cox, John P. Gibbs, Megan A. Gibbs, Heather Hatch, Cornelis E.C.A. Hop, Ilana N. Kasman, Jennifer LaPerle, JianHua Liu, Xingrong Liu, Michael Logman, Debra Maclin, Frank M. Nedza, Frederick Nelson, Emily Olson, Sandhya Rahematpura, David Raunig, Sabrinia Rogers, Kari Schmidt, Douglas K. Spracklin, Mark Szewc, Matthew Troutman, Elaine Tseng, Meihua Tu, Jeffrey W. Van Deusen, Karthik Venkatakrishnan, Gary Walens, Ellen Q. Wang, Diane Wong, Adam S. Yasgar, and Chenghong Zhang

THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL
Drug Metab Dispos 2005 33: 165-174. Published online October 22, 2004; 10.1124/dmd.104.001230 [Abstract] [Full Text] [PDF]  

Tristan S. Maurer, Demetria B. DeBartolo, David A. Tess, and Dennis O. Scott

RELATIONSHIP BETWEEN EXPOSURE AND NONSPECIFIC BINDING OF THIRTY-THREE CENTRAL NERVOUS SYSTEM DRUGS IN MICE
Drug Metab Dispos 2005 33: 175-181. Published online October 22, 2004; 10.1124/dmd.104.001222 [Abstract] [Full Text] [PDF]  

Lisa M. Augustine, Robert J. Markelewicz, Jr., Kim Boekelheide, and Nathan J. Cherrington

XENOBIOTIC AND ENDOBIOTIC TRANSPORTER MRNA EXPRESSION IN THE BLOOD-TESTIS BARRIER
Drug Metab Dispos 2005 33: 182-189. Published online October 19, 2004; 10.1124/dmd.104.001024 [Abstract] [Full Text] [PDF]  

S. Cyrus Khojasteh-Bakht, John P. O'Donnell, Hassan G. Fouda, and Michael J. Potchoiba

METABOLISM, PHARMACOKINETICS, TISSUE DISTRIBUTION, AND EXCRETION OF [¹⁴C]CP-424391 IN RATS
Drug Metab Dispos 2005 33: 190-199. Published online October 14, 2004; 10.1124/dmd.104.001065 [Abstract] [Full Text] [PDF]  

Commentaries:

Lichuan Liu and K. Sandy Pang

THE ROLES OF TRANSPORTERS AND ENZYMES IN HEPATIC DRUG PROCESSING
Drug Metab Dispos 2005 33: 1-9. Published online October 1, 2004; 10.1124/dmd.104.001149 [Abstract] [Full Text] [PDF]  

The 2004 Bernard B. Brodie Award Lecture:

Thomas L. Poulos

STRUCTURAL AND FUNCTIONAL DIVERSITY IN HEME MONOOXYGENASES
Drug Metab Dispos 2005 33: 10-18. Published online October 8, 2004; 10.1124/dmd.104.002071 [Abstract] [Full Text] [PDF]  

Short Communications:

Chia-ting Yu, Jie Chen, Xiao Wei Teng, Vincent Tong, and Thomas K. H. Chang

LACK OF EVIDENCE FOR INDUCTION OF CYP2B1, CYP3A23, AND CYP1A2 GENE EXPRESSION BY Panax ginseng AND Panax quinquefolius EXTRACTS IN ADULT RATS AND PRIMARY CULTURES OF RAT HEPATOCYTES
Drug Metab Dispos 2005 33: 19-22. Published online October 1, 2004; 10.1124/dmd.104.001917 [Abstract] [Full Text] [PDF]  

Errata:

CORRECTION TO "TISSUE DISTRIBUTION, STABILITY, AND PHARMACOKINETICS OF APO2 LIGAND/TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND IN HUMAN COLON CARCINOMA COLO205 TUMOR-BEARING MICE"
Drug Metab Dispos 2005 33: 200-201. [Full Text] [PDF]  

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