Articles:

Liyue Huang, Yi Wang, and Scott Grimm

ATP-DEPENDENT TRANSPORT OF ROSUVASTATIN IN MEMBRANE VESICLES EXPRESSING BREAST CANCER RESISTANCE PROTEIN
Drug Metab Dispos 2006 34: 738-742. Published online January 13, 2006; 10.1124/dmd.105.007534 [Abstract] [Full Text] [PDF]  

Harunobu Tahara, Hiroyuki Kusuhara, Kazuya Maeda, Hermann Koepsell, Eiichi Fuse, and Yuichi Sugiyama

INHIBITION OF OAT3-MEDIATED RENAL UPTAKE AS A MECHANISM FOR DRUG-DRUG INTERACTION BETWEEN FEXOFENADINE AND PROBENECID
Drug Metab Dispos 2006 34: 743-747. Published online February 2, 2006; 10.1124/dmd.105.008375 [Abstract] [Full Text] [PDF]  

Z. Yan, G. W. Caldwell, D. Gauthier, G. C. Leo, J. Mei, C. Y. Ho, W. J. Jones, J. A. Masucci, R. W. Tuman, R. A. Galemmo, Jr., and D. L. Johnson

N-GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES
Drug Metab Dispos 2006 34: 748-755. Published online February 2, 2006; 10.1124/dmd.106.009274 [Abstract] [Full Text] [PDF]  

Tiangang Li and John Y. L. Chiang

RIFAMPICIN INDUCTION OF CYP3A4 REQUIRES PREGNANE X RECEPTOR CROSS TALK WITH HEPATOCYTE NUCLEAR FACTOR 4 AND COACTIVATORS, AND SUPPRESSION OF SMALL HETERODIMER PARTNER GENE EXPRESSION
Drug Metab Dispos 2006 34: 756-764. Published online February 2, 2006; 10.1124/dmd.105.007575 [Abstract] [Full Text] [PDF]  

Markus Zollinger, Felix Waldmeier, Stefan Hartmann, Gerhard Zenke, Alfred G. Zimmerlin, Ulrike Glaenzel, Jean-Pierre Baldeck, Alain Schweitzer, Stephane Berthier, Thomas Moenius, and Maximilian A. Grassberger

PIMECROLIMUS: ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION IN HEALTHY VOLUNTEERS AFTER A SINGLE ORAL DOSE AND SUPPLEMENTARY INVESTIGATIONS IN VITRO
Drug Metab Dispos 2006 34: 765-774. Published online February 7, 2006; 10.1124/dmd.105.007732 [Abstract] [Full Text] [PDF]  

Ulf G. Eriksson, Hassan Dorani, Johan Karlsson, Holger Fritsch, Kurt-Jürgen Hoffmann, Lis Olsson, Troy C. Sarich, Ulrika Wall, and Kajs-Marie Schützer

INFLUENCE OF ERYTHROMYCIN ON THE PHARMACOKINETICS OF XIMELAGATRAN MAY INVOLVE INHIBITION OF P-GLYCOPROTEIN-MEDIATED EXCRETION
Drug Metab Dispos 2006 34: 775-782. Published online February 2, 2006; 10.1124/dmd.105.008607 [Abstract] [Full Text] [PDF]  

Joseph D. Ma, Anne N. Nafziger, Gerry Rhodes, Siyu Liu, and Joseph S. Bertino, Jr.

DURATION OF PLECONARIL EFFECT ON CYTOCHROME P450 3A ACTIVITY IN HEALTHY ADULTS USING THE ORAL BIOMARKER MIDAZOLAM
Drug Metab Dispos 2006 34: 783-785. Published online February 7, 2006; 10.1124/dmd.105.007831 [Abstract] [Full Text] [PDF]  

Jarkko Rautio, Joan E. Humphreys, Lindsey O. Webster, Anand Balakrishnan, John P. Keogh, Jeevan R. Kunta, Cosette J. Serabjit-Singh, and Joseph W. Polli

IN VITRO P-GLYCOPROTEIN INHIBITION ASSAYS FOR ASSESSMENT OF CLINICAL DRUG INTERACTION POTENTIAL OF NEW DRUG CANDIDATES: A RECOMMENDATION FOR PROBE SUBSTRATES
Drug Metab Dispos 2006 34: 786-792. Published online February 2, 2006; 10.1124/dmd.105.008615 [Abstract] [Full Text] [PDF]  

Rikiya Ohashi, Yukari Kamikozawa, Mika Sugiura, Hajime Fukuda, Hikaru Yabuuchi, and Ikumi Tamai

EFFECT OF P-GLYCOPROTEIN ON INTESTINAL ABSORPTION AND BRAIN PENETRATION OF ANTIALLERGIC AGENT BEPOTASTINE BESILATE
Drug Metab Dispos 2006 34: 793-799. Published online February 2, 2006; 10.1124/dmd.105.007559 [Abstract] [Full Text] [PDF]  

Daisuke Tenmizu, Kiyoshi Noguchi, Hidetaka Kamimura, Hisakazu Ohtani, and Yasufumi Sawada

THE CANINE CYP1A2 DEFICIENCY POLYMORPHISM DRAMATICALLY AFFECTS THE PHARMACOKINETICS OF 4-CYCLOHEXYL-1-ETHYL-7-METHYLPYRIDO[2,3-D]-PYRIMIDINE-2-(1H)-ONE (YM-64227), A PHOSPHODIESTERASE TYPE 4 INHIBITOR
Drug Metab Dispos 2006 34: 800-806. Published online February 10, 2006; 10.1124/dmd.105.008722 [Abstract] [Full Text] [PDF]  

Wenying Li, Donglu Zhang, Lifei Wang, Hao Zhang, Peter T. Cheng, Duxi Zhang, Donald W. Everett, and W. Griffith Humphreys

BIOTRANSFORMATION OF CARBON-14-LABELED MURAGLITAZAR IN MALE MICE: INTERSPECIES DIFFERENCE IN METABOLIC PATHWAYS LEADING TO UNIQUE METABOLITES
Drug Metab Dispos 2006 34: 807-820. Published online February 7, 2006; 10.1124/dmd.105.007856 [Abstract] [Full Text] [PDF]  

Yune-Fang Ueng, Ming-Jaw Don, Woan-Ching Jan, Shu-Yun Wang, Li-Kang Ho, and Chieh-Fu Chen

OXIDATIVE METABOLISM OF THE ALKALOID RUTAECARPINE BY HUMAN CYTOCHROME P450
Drug Metab Dispos 2006 34: 821-827. Published online February 24, 2006; 10.1124/dmd.105.007849 [Abstract] [Full Text] [PDF]  

Rika Goda, Daichi Nagai, Yuji Akiyama, Kiyohiro Nishikawa, Isao Ikemoto, Yoshio Aizawa, Kiyoshi Nagata, and Yasushi Yamazoe

DETECTION OF A NEW N-OXIDIZED METABOLITE OF FLUTAMIDE, N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]HYDROXYLAMINE, IN HUMAN LIVER MICROSOMES AND URINE OF PROSTATE CANCER PATIENTS
Drug Metab Dispos 2006 34: 828-835. Published online February 28, 2006; 10.1124/dmd.105.008623 [Abstract] [Full Text] [PDF]  

Yang Dai, Mary F. Hebert, Nina Isoherranen, Connie L. Davis, Christopher Marsh, Danny D. Shen, and Kenneth E. Thummel

EFFECT OF CYP3A5 POLYMORPHISM ON TACROLIMUS METABOLIC CLEARANCE IN VITRO
Drug Metab Dispos 2006 34: 836-847. Published online February 24, 2006; 10.1124/dmd.105.008680 [Abstract] [Full Text] [PDF]  

Michael A. Terner, W. James Gilmore, Yanping Lou, and E. James Squires

THE ROLE OF CYP2A AND CYP2E1 IN THE METABOLISM OF 3-METHYLINDOLE IN PRIMARY CULTURED PORCINE HEPATOCYTES
Drug Metab Dispos 2006 34: 848-854. Published online February 24, 2006; 10.1124/dmd.105.008128 [Abstract] [Full Text] [PDF]  

Stacey Becker and Xingrong Liu

EVALUATION OF THE UTILITY OF BRAIN SLICE METHODS TO STUDY BRAIN PENETRATION
Drug Metab Dispos 2006 34: 855-861. Published online February 24, 2006; 10.1124/dmd.105.007914 [Abstract] [Full Text] [PDF]  

Rie Nakagomi-Hagihara, Daisuke Nakai, Kenji Kawai, Yasushi Yoshigae, Taro Tokui, Takaaki Abe, and Toshihiko Ikeda

OATP1B1, OATP1B3, AND MRP2 ARE INVOLVED IN HEPATOBILIARY TRANSPORT OF OLMESARTAN, A NOVEL ANGIOTENSIN II BLOCKER
Drug Metab Dispos 2006 34: 862-869. Published online February 24, 2006; 10.1124/dmd.105.008888 [Abstract] [Full Text] [PDF]  

Lysiane Richert, Michael J. Liguori, Catherine Abadie, Bruno Heyd, Georges Mantion, Nermin Halkic, and Jeffrey F. Waring

GENE EXPRESSION IN HUMAN HEPATOCYTES IN SUSPENSION AFTER ISOLATION IS SIMILAR TO THE LIVER OF ORIGIN, IS NOT AFFECTED BY HEPATOCYTE COLD STORAGE AND CRYOPRESERVATION, BUT IS STRONGLY CHANGED AFTER HEPATOCYTE PLATING
Drug Metab Dispos 2006 34: 870-879. Published online February 10, 2006; 10.1124/dmd.105.007708 [Abstract] [Full Text] [PDF] [Data Supplement]   

Mary F. Paine, Heather L. Hart, Shana S. Ludington, Robert L. Haining, Allan E. Rettie, and Darryl C. Zeldin

THE HUMAN INTESTINAL CYTOCHROME P450 "PIE"
Drug Metab Dispos 2006 34: 880-886. Published online February 7, 2006; 10.1124/dmd.105.008672 [Abstract] [Full Text] [PDF]  

John R. Atack, Andy Pike, Ashley Clarke, Susan M. Cook, Bindi Sohal, Ruth M. McKernan, and Gerard R. Dawson

RAT PHARMACOKINETICS AND PHARMACODYNAMICS OF A SUSTAINED RELEASE FORMULATION OF THE GABA_A 5-SELECTIVE COMPOUND L-655,708
Drug Metab Dispos 2006 34: 887-893. Published online February 2, 2006; 10.1124/dmd.105.006973 [Abstract] [Full Text] [PDF]  

Short Communications:

Natalie L. Trevaskis, Christopher J.H. Porter, and William N. Charman

AN EXAMINATION OF THE INTERPLAY BETWEEN ENTEROCYTE-BASED METABOLISM AND LYMPHATIC DRUG TRANSPORT IN THE RAT
Drug Metab Dispos 2006 34: 729-733. Published online February 7, 2006; 10.1124/dmd.105.008102 [Abstract] [Full Text] [PDF]  

J. George Zhang, Shangara S. Dehal, Thuy Ho, Jennifer Johnson, Catherine Chandler, Andrew P. Blanchard, Robert J. Clark, Jr., Charles L. Crespi, David M. Stresser, and James Wong

HUMAN CYTOCHROME P450 INDUCTION AND INHIBITION POTENTIAL OF CLEVIDIPINE AND ITS PRIMARY METABOLITE H152/81
Drug Metab Dispos 2006 34: 734-737. Published online February 24, 2006; 10.1124/dmd.105.006569 [Abstract] [Full Text] [PDF]  

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