Articles:

Maria G. Beconi, James R. Reed, Yohannes Teffera, Yuan-Qing Xia, Christopher J. Kochansky, David Q. Liu, Shiyao Xu, Charles S. Elmore, Suzanne Ciccotto, Donald F. Hora, Ralph A. Stearns, and Stella H. Vincent

Disposition of the Dipeptidyl Peptidase 4 Inhibitor Sitagliptin in Rats and Dogs
Drug Metab Dispos 2007 35: 525-532. Published online January 12, 2007; 10.1124/dmd.106.013110 [Abstract] [Full Text] [PDF]  

Stella H. Vincent, James R. Reed, Arthur J. Bergman, Charles S. Elmore, Bing Zhu, Shiyao Xu, David Ebel, Patrick Larson, Wei Zeng, Li Chen, Stacy Dilzer, Kenneth Lasseter, Keith Gottesdiener, John A. Wagner, and Gary A. Herman

Metabolism And Excretion of the Dipeptidyl Peptidase 4 Inhibitor [¹⁴C]Sitagliptin in Humans
Drug Metab Dispos 2007 35: 533-538. Published online January 12, 2007; 10.1124/dmd.106.013136 [Abstract] [Full Text] [PDF]  

Jie Cao, Xiao Chen, Jun Liang, Xue-Qing Yu, An-Long Xu, Eli Chan, Duan Wei, Min Huang, Jing-Yuan Wen, Xi-Yong Yu, Xiao-Tian Li, Fwu-Shan Sheu, and Shu-Feng Zhou

Role of P-glycoprotein in the Intestinal Absorption of Glabridin, an Active Flavonoid from the Root of Glycyrrhiza glabra
Drug Metab Dispos 2007 35: 539-553. Published online January 12, 2007; 10.1124/dmd.106.010801 [Abstract] [Full Text] [PDF]  

G. S. J. Mannens, J. Hendrickx, C. G. M. Janssen, S. Chien, B. Van Hoof, T. Verhaeghe, M. Kao, M. F. Kelley, I. Goris, M. Bockx, B. Verreet, M. Bialer, and W. Meuldermans

The Absorption, Metabolism, and Excretion of the Novel Neuromodulator RWJ-333369 (1,2-Ethanediol, [1-2-Chlorophenyl]-, 2-carbamate, [S]-) in Humans
Drug Metab Dispos 2007 35: 554-565. Published online August 25, 2006; 10.1124/dmd.106.011940 [Abstract] [Full Text] [PDF]  

Rao N. V. S. Mamidi, Geert Mannens, Pieter Annaert, Jan Hendrickx, Ivo Goris, Mark Bockx, Cor G. M. Janssen, Mark Kao, Michael F. Kelley, and Willem Meuldermans

Metabolism and Excretion of RWJ-333369 [1,2-Ethanediol, 1-(2-Chlorophenyl)-, 2-carbamate, (S)-] in Mice, Rats, Rabbits, and Dogs
Drug Metab Dispos 2007 35: 566-575. Published online January 12, 2007; 10.1124/dmd.106.012336 [Abstract] [Full Text] [PDF]  

Cindy Q. Xia, Ning Liu, Gerald T. Miwa, and Liang-Shang Gan

Interactions of Cyclosporin A with Breast Cancer Resistance Protein
Drug Metab Dispos 2007 35: 576-582. Published online January 12, 2007; 10.1124/dmd.106.011866 [Abstract] [Full Text] [PDF]  

Miki Katoh, Tomohito Matsui, and Tsuyoshi Yokoi

Glucuronidation of Antiallergic Drug, Tranilast: Identification of Human UDP-Glucuronosyltransferase Isoforms and Effect of Its Phase I Metabolite
Drug Metab Dispos 2007 35: 583-589. Published online January 12, 2007; 10.1124/dmd.106.013706 [Abstract] [Full Text] [PDF]  

Yvonne Meier, Jyrki J. Eloranta, Jutta Darimont, Manfred G. Ismair, Christian Hiller, Michael Fried, Gerd A. Kullak-Ublick, and Stephan R. Vavricka

Regional Distribution of Solute Carrier mRNA Expression Along the Human Intestinal Tract
Drug Metab Dispos 2007 35: 590-594. Published online January 12, 2007; 10.1124/dmd.106.013342 [Abstract] [Full Text] [PDF] [Data Supplement]   

Denis A. Evseenko, James W. Paxton, and Jeffrey A. Keelan

Independent Regulation of Apical and Basolateral Drug Transporter Expression and Function in Placental Trophoblasts by Cytokines, Steroids, and Growth Factors
Drug Metab Dispos 2007 35: 595-601. Published online January 19, 2007; 10.1124/dmd.106.011478 [Abstract] [Full Text] [PDF]  

Yuji Mano, Takashi Usui, and Hidetaka Kamimura

Comparison of Inhibition Potentials of Drugs against Zidovudine Glucuronidation in Rat Hepatocytes and Liver Microsomes
Drug Metab Dispos 2007 35: 602-606. Published online January 31, 2007; 10.1124/dmd.106.014225 [Abstract] [Full Text] [PDF]  

Ge Lin, Jun Tang, Xiao Quan Liu, Yan Jiang, and Jiang Zheng

Deacetylclivorine: A Gender-Selective Metabolite of Clivorine Formed in Female Sprague-Dawley Rat Liver Microsomes
Drug Metab Dispos 2007 35: 607-613. Published online January 19, 2007; 10.1124/dmd.106.014100 [Abstract] [Full Text] [PDF]  

Charles W. Locuson, J. Matthew Hutzler, and Timothy S. Tracy

Visible Spectra of Type II Cytochrome P450-Drug Complexes: Evidence that "Incomplete" Heme Coordination Is Common
Drug Metab Dispos 2007 35: 614-622. Published online January 24, 2007; 10.1124/dmd.106.012609 [Abstract] [Full Text] [PDF]  

Sang Seop Lee, Hye-Eun Jeong, Joo-Mi Yi, Hyun-Ju Jung, Jae-Eun Jang, Eun-Young Kim, Su-Jun Lee, and Jae-Gook Shin

Identification and Functional Assessment of BCRP Polymorphisms in a Korean Population
Drug Metab Dispos 2007 35: 623-632. Published online January 19, 2007; 10.1124/dmd.106.012302 [Abstract] [Full Text] [PDF]  

Harvey J. Armbrecht, Vijaya M. Lakshmi, Jason Wickstra, Fong Fu Hsu, and Terry V. Zenser

Metabolism of a Heterocyclic Amine Colon Carcinogen in Young and Old Rats
Drug Metab Dispos 2007 35: 633-639. Published online January 24, 2007; 10.1124/dmd.106.013532 [Abstract] [Full Text] [PDF]  

Jeroen Kool, Sebastiaan M. van Liempd, Huub van Rossum, Danny A. van Elswijk, Hubertus Irth, Jan N. M. Commandeur, and Nico P. E. Vermeulen

Development of Three Parallel Cytochrome P450 Enzyme Affinity Detection Systems Coupled On-line to Gradient High-Performance Liquid Chromatography
Drug Metab Dispos 2007 35: 640-648. Published online January 24, 2007; 10.1124/dmd.106.012245 [Abstract] [Full Text] [PDF]  

Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Ron A. Gilissen, Claire E. Mackie, and Marjoleen J. Nijsen

The Prediction of Drug Metabolism, Tissue Distribution, and Bioavailability of 50 Structurally Diverse Compounds in Rat Using Mechanism-Based Absorption, Distribution, and Metabolism Prediction Tools
Drug Metab Dispos 2007 35: 649-659. Published online January 31, 2007; 10.1124/dmd.106.014027 [Abstract] [Full Text] [PDF]  

J. Cory Kalvass, Tristan S. Maurer, and Gary M. Pollack

Use of Plasma and Brain Unbound Fractions to Assess the Extent of Brain Distribution of 34 Drugs: Comparison of Unbound Concentration Ratios to in Vivo P-Glycoprotein Efflux Ratios
Drug Metab Dispos 2007 35: 660-666. Published online January 19, 2007; 10.1124/dmd.106.012294 [Abstract] [Full Text] [PDF]  

Ho-Jin Kang, Im-Sook Song, Ho Jung Shin, Woo-Young Kim, Choong-Hee Lee, Joo-Cheol Shim, Hong-Hao Zhou, Sang Seop Lee, and Jae-Gook Shin

Identification and Functional Characterization of Genetic Variants of Human Organic Cation Transporters in a Korean Population
Drug Metab Dispos 2007 35: 667-675. Published online January 12, 2007; 10.1124/dmd.106.013581 [Abstract] [Full Text] [PDF]  

Sanjoy Roychowdhury, Piyush M. Vyas, and Craig K. Svensson

Formation and Uptake of Arylhydroxylamine-Haptenated Proteins in Human Dendritic Cells
Drug Metab Dispos 2007 35: 676-681. Published online January 12, 2007; 10.1124/dmd.106.013680 [Abstract] [Full Text] [PDF]  

Tracy C. DeLozier, Grace E. Kissling, Sherry J. Coulter, Diana Dai, Julie F. Foley, J. Alyce Bradbury, Elizabeth Murphy, Charles Steenbergen, Darryl C. Zeldin, and Joyce A. Goldstein

Detection of Human CYP2C8, CYP2C9, and CYP2J2 in Cardiovascular Tissues
Drug Metab Dispos 2007 35: 682-688. Published online January 12, 2007; 10.1124/dmd.106.012823 [Abstract] [Full Text] [PDF]  

Weihua Li, Hong Liu, Xiaomin Luo, Weiliang Zhu, Yun Tang, James R. Halpert, and Hualiang Jiang

Possible Pathway(s) of Metyrapone Egress from the Active Site of Cytochrome P450 3A4: A Molecular Dynamics Simulation
Drug Metab Dispos 2007 35: 689-696. Published online January 24, 2007; 10.1124/dmd.106.014019 [Abstract] [Full Text] [PDF]  

Short Communications:

Albert Braeuning, Carina Ittrich, Christoph Köhle, Albrecht Buchmann, and Michael Schwarz

Zonal Gene Expression in Mouse Liver Resembles Expression Patterns of Ha-ras and ß-Catenin Mutated Hepatomas
Drug Metab Dispos 2007 35: 503-507. Published online January 12, 2007; 10.1124/dmd.106.013656 [Abstract] [Full Text] [PDF] [Data Supplement]   

Eriko Higashi, Miki Nakajima, Miki Katoh, Shogo Tokudome, and Tsuyoshi Yokoi

Inhibitory Effects of Neurotransmitters and Steroids on Human CYP2A6
Drug Metab Dispos 2007 35: 508-514. Published online January 19, 2007; 10.1124/dmd.106.014084 [Abstract] [Full Text] [PDF]  

Tatsuki Fukami, Miki Nakajima, Hiroyuki Yamanaka, Yasunari Fukushima, Howard L. Mcleod, and Tsuyoshi Yokoi

A Novel Duplication Type of CYP2A6 Gene in African-American Population
Drug Metab Dispos 2007 35: 515-520. Published online January 31, 2007; 10.1124/dmd.106.013557 [Abstract] [Full Text] [PDF]  

David Q. Liu, Byron H. Arison, Ralph A. Stearns, Dooseop Kim, and Stella H. Vincent

Characterization of Two Cyclic Metabolites of Sitagliptin
Drug Metab Dispos 2007 35: 521-524. Published online January 12, 2007; 10.1124/dmd.106.013128 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Dennis A. Smith, Maurice Dickins, Odette A. Fahmi, Kazuhide Iwasaki, Caroline Lee, R. Scott Obach, Guy Padbury, Sonia M. De Morais, Sharon L. Ripp, Jeff Stevens, Richard Voorman, and Kuresh Youdim

The Time to Move Cytochrome P450 Induction into Mainstream Pharmacology Is Long Overdue
Drug Metab Dispos 2007 35: 697-698. [Full Text] [PDF]  

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