DMD -- Table of Contents (36 [1])

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January 2008; 36 (1)   [Index by Author] [Cover Caption]

       Centennial Perspective

       Articles

       Short Communications

       Erratum

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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Centennial Perspective:

Patrick J. Murphy: The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 1, 1909–1958
Drug Metab Dispos 2008 36: 1-5. Published online July 30, 2007; 10.1124/dmd.107.017079 [Abstract] [Full Text] [PDF] [Erratum]

Articles:

Hong Lu and Curtis Klaassen: Gender Differences in mRNA Expression of ATP-Binding Cassette Efflux and Bile Acid Transporters in Kidney, Liver, and Intestine of 5/6 Nephrectomized Rats
Drug Metab Dispos 2008 36: 16-23. Published online September 12, 2007; 10.1124/dmd.107.014845 [Abstract] [Full Text] [PDF]

Mingshe Zhu, Daisy B. Whigan, Shu Y. Chang, and Randy C. Dockens: Disposition and Metabolism of [¹⁴C]Brasofensine in Rats, Monkeys, and Humans
Drug Metab Dispos 2008 36: 24-35. Published online October 1, 2007; 10.1124/dmd.107.016139 [Abstract] [Full Text] [PDF]

Maria Laura Sargentini-Maier, Pascal Espié, Alain Coquette, and Armel Stockis: Pharmacokinetics and Metabolism of ¹⁴C-Brivaracetam, a Novel SV2A Ligand, in Healthy Subjects
Drug Metab Dispos 2008 36: 36-45. Published online October 1, 2007; 10.1124/dmd.107.017129 [Abstract] [Full Text] [PDF]

Ian S. Westley, Raymond G. Morris, Allan M. Evans, and Benedetta C. Sallustio: Glucuronidation of Mycophenolic Acid by Wistar and Mrp2-Deficient TR^- Rat Liver Microsomes
Drug Metab Dispos 2008 36: 46-50. Published online October 1, 2007; 10.1124/dmd.107.017210 [Abstract] [Full Text] [PDF]

Yoshihisa Kato, Shin-ichi Ikushiro, Yoshikazu Emi, Sekihiro Tamaki, Hiroshi Suzuki, Toshiyuki Sakaki, Shizuo Yamada, and Masakuni Degawa: Hepatic UDP-Glucuronosyltransferases Responsible for Glucuronidation of Thyroxine in Humans
Drug Metab Dispos 2008 36: 51-55. Published online October 1, 2007; 10.1124/dmd.107.018184 [Abstract] [Full Text] [PDF]

Gang Chen, Rebecca-Ayme Cue, Kerstin Lundstrom, Jeffrey D. Wood, and Olena Doran: Regulation of CYP2A6 Protein Expression by Skatole, Indole, and Testicular Steroids in Primary Cultured Pig Hepatocytes
Drug Metab Dispos 2008 36: 56-60. Published online October 1, 2007; 10.1124/dmd.107.017285 [Abstract] [Full Text] [PDF]

Xianbin Tian, Maciej J. Zamek-Gliszczynski, Jun Li, Arlene S. Bridges, Ken-ichi Nezasa, Nita J. Patel, Thomas J. Raub, and Kim L. R. Brouwer: Multidrug Resistance-Associated Protein 2 Is Primarily Responsible for the Biliary Excretion of Fexofenadine in Mice
Drug Metab Dispos 2008 36: 61-64. Published online October 3, 2007; 10.1124/dmd.107.017319 [Abstract] [Full Text] [PDF]

Zhiming Wen, Todd E. Dumas, Sarah J. Schrieber, Roy L. Hawke, Michael W. Fried, and Philip C. Smith: Pharmacokinetics and Metabolic Profile of Free, Conjugated, and Total Silymarin Flavonolignans in Human Plasma after Oral Administration of Milk Thistle Extract
Drug Metab Dispos 2008 36: 65-72. Published online October 3, 2007; 10.1124/dmd.107.017566 [Abstract] [Full Text] [PDF]

Aleksi Tornio, Mikko Niemi, Pertti J. Neuvonen, and Janne T. Backman: Trimethoprim and the CYP2C8^*3 Allele Have Opposite Effects on the Pharmacokinetics of Pioglitazone
Drug Metab Dispos 2008 36: 73-80. Published online October 3, 2007; 10.1124/dmd.107.018010 [Abstract] [Full Text] [PDF]

Ken-ichi Kaneko, Hikaru Fukuda, Victor Tuan Giam Chuang, Keishi Yamasaki, Kohichi Kawahara, Hitoshi Nakayama, Ayaka Suenaga, Toru Maruyama, and Masaki Otagiri: Subdomain IIIA of Dog Albumin Contains a Binding Site Similar to Site II of Human Albumin
Drug Metab Dispos 2008 36: 81-86. Published online October 9, 2007; 10.1124/dmd.107.016873 [Abstract] [Full Text] [PDF]

A. Collett, R. H. Stephens, M. D. Harwood, M. Humphrey, L. Dallman, J. Bennett, J. Davis, G. L. Carlson, and G. Warhurst: Investigation of Regional Mechanisms Responsible for Poor Oral Absorption in Humans of a Modified Release Preparation of the ${alpha}$ -Adrenoreceptor Antagonist, 4-Amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): The Rational Use of ex Vivo Intestine to Predict in Vivo Absorption
Drug Metab Dispos 2008 36: 87-94. Published online October 11, 2007; 10.1124/dmd.107.016865 [Abstract] [Full Text] [PDF]

Romi Ghose, Damara White, Tao Guo, Jesus Vallejo, and Saul J. Karpen: Regulation of Hepatic Drug-Metabolizing Enzyme Genes by Toll-Like Receptor 4 Signaling Is Independent of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein
Drug Metab Dispos 2008 36: 95-101. Published online October 11, 2007; 10.1124/dmd.107.018051 [Abstract] [Full Text] [PDF]

Huadong Sun and K. Sandy Pang: Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study
Drug Metab Dispos 2008 36: 102-123. Published online October 11, 2007; 10.1124/dmd.107.015321 [Abstract] [Full Text] [PDF]

Judith Naud, Josée Michaud, Francois A. Leblond, Stéphane Lefrancois, Alain Bonnardeaux, and Vincent Pichette: Effects of Chronic Renal Failure on Liver Drug Transporters
Drug Metab Dispos 2008 36: 124-128. Published online October 16, 2007; 10.1124/dmd.107.018192 [Abstract] [Full Text] [PDF]

Anna M. Furimsky, Carol E. Green, Lewanne E. Hunt Sharp, Paul Catz, Araba A. Adjei, Toufan Parman, Izet M. Kapetanovic, Richard M. Weinshilboum, and Lalitha V. Iyer: Effect of Resveratrol on 17β-Estradiol Sulfation by Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
Drug Metab Dispos 2008 36: 129-136. Published online October 22, 2007; 10.1124/dmd.107.016725 [Abstract] [Full Text] [PDF]

Kajsa P. Kanebratt and Tommy B. Andersson: HepaRG Cells as an in Vitro Model for Evaluation of Cytochrome P450 Induction in Humans
Drug Metab Dispos 2008 36: 137-145. Published online October 22, 2007; 10.1124/dmd.107.017418 [Abstract] [Full Text] [PDF]

Nina Isoherranen, Shana R. Ludington, Raymond C. Givens, Jatinder K. Lamba, Susan N. Pusek, E. Claire Dees, David K. Blough, Kazunori Iwanaga, Roy L. Hawke, Erin G. Schuetz, Paul B. Watkins, Kenneth E. Thummel, and Mary F. Paine: The Influence of CYP3A5 Expression on the Extent of Hepatic CYP3A Inhibition Is Substrate-Dependent: An in Vitro-in Vivo Evaluation
Drug Metab Dispos 2008 36: 146-154. Published online October 22, 2007; 10.1124/dmd.107.018382 [Abstract] [Full Text] [PDF]

Jaya S. Kartha and Garold S. Yost: Mechanism-Based Inactivation of Lung-Selective Cytochrome P450 CYP2F Enzymes
Drug Metab Dispos 2008 36: 155-162. Published online October 25, 2007; 10.1124/dmd.107.017897 [Abstract] [Full Text] [PDF]

Frank T. Peters, Markus R. Meyer, Denis S. Theobald, and Hans H. Maurer: Identification of Cytochrome P450 Enzymes Involved in the Metabolism of the New Designer Drug 4'-Methyl- ${alpha}$ -pyrrolidinobutyrophenone
Drug Metab Dispos 2008 36: 163-168. Published online October 25, 2007; 10.1124/dmd.107.017293 [Abstract] [Full Text] [PDF]

Jatinder Lamba, Vishal Lamba, Stephen Strom, Raman Venkataramanan, and Erin Schuetz: Novel Single Nucleotide Polymorphisms in the Promoter and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression
Drug Metab Dispos 2008 36: 169-181. Published online October 9, 2007; 10.1124/dmd.107.016600 [Abstract] [Full Text] [PDF]

Gérard Siest, Elise Jeannesson, Jean-Brice Marteau, Anastasia Samara, Bérangère Marie, Michèle Pfister, and Sophie Visvikis-Siest: Transcription Factor and Drug-Metabolizing Enzyme Gene Expression in Lymphocytes from Healthy Human Subjects
Drug Metab Dispos 2008 36: 182-189. Published online October 16, 2007; 10.1124/dmd.107.017228 [Abstract] [Full Text] [PDF]

Laure Poquet, Michael N. Clifford, and Gary Williamson: Transport and Metabolism of Ferulic Acid through the Colonic Epithelium
Drug Metab Dispos 2008 36: 190-197. Published online October 22, 2007; 10.1124/dmd.107.017558 [Abstract] [Full Text] [PDF]

Daniel A. J. Bow, Jennifer L. Perry, David S. Miller, John B. Pritchard, and Kim L. R. Brouwer: Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in Freshly Isolated Rat Hepatocytes
Drug Metab Dispos 2008 36: 198-202. Published online October 22, 2007; 10.1124/dmd.107.018200 [Abstract] [Full Text] [PDF]

Short Communications:

Kaori Morimoto, Masanori Nakakariya, Yoshiyuki Shirasaka, Chihaya Kakinuma, Takuya Fujita, Ikumi Tamai, and Takuo Ogihara: Oseltamivir (Tamiflu) Efflux Transport at the Blood-Brain Barrier via P-Glycoprotein
Drug Metab Dispos 2008 36: 6-9. Published online October 16, 2007; 10.1124/dmd.107.017699 [Abstract] [Full Text] [PDF]

Jason M. Gow, Leslie W. Chinn, and Deanna L. Kroetz: The Effects of ABCB1 3'-Untranslated Region Variants on mRNA Stability
Drug Metab Dispos 2008 36: 10-15. Published online October 16, 2007; 10.1124/dmd.107.017087 [Abstract] [Full Text] [PDF]

Erratum:

: CORRECTION TO "USE OF ISOLATED HEPATOCYTE PREPARATIONS FOR CYTOCHROME P450 INHIBITION STUDIES: COMPARISON WITH MICROSOMES FOR K_I DETERMINATION"
Drug Metab Dispos 2008 36: 203. [Full Text] [PDF]

Cover Caption:

About the cover: Cister analysis of PXR (Fig. 1D). Regions with clusters of binding sites for liver-enriched transcription factors and hormone receptors are indicated. See article by Lamba et al. on page 169 of this issue.