RT Journal Article
SR Electronic
T1 Metabolism of Carbidopa [L-(-)-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic Acid Monohydrate], an Aromatic Amino Acid Decarboxylase Inhibitor, in the Rat, Dog, Rhesus Monkey, and Man
JF Drug Metabolism and Disposition
JO Drug Metab Dispos
FD American Society for Pharmacology and Experimental Therapeutics
SP 399
OP 399
VO 2
IS 4
A1 S. Vickers
A1 E. K. Stuart
A1 J. R. Bianchine
A1 H. B. Hucker
A1 M. E. Jaffe
A1 R. E. Rhodes
A1 W. J. A. VandenHeuvel
YR 1974
UL http://dmd.aspetjournals.org/content/2/4/399.1.abstract
AB In "Metabolism of Carbidopa [L-(-)-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic Acid Monohydrate], an Aromatic Amino Acid Decarboxylase Inhibitor, in the Rat, Dog, Rhesus Monkey, and Man," by S. Vickers, E. K. Stuart, J. R. Bianchine, H. B. Hucker, M. E. Jaffe, R. E. Rhodes, and W. J. A. VandenHeuvel, in the January/February 1974 issue of Drug Metabolism and Disposition, vol. 2, no. 1, pp. 9-22, the second sentence of the introduction on p. 9 should read as follows (changed word in italics): It is of interest in the therapy of Parkinson's disease as a means of inhibiting the extracerebral metabolism of L-dopa and thus decreasing the dosage requirement of L-dopa and possibly, therefore, decreasing those side effects which are secondary to high levels of the amino acid in the periphery (2-5). Copyright © 1974 by The American Society for Pharmacology and Experimental Therapeutics