TY - JOUR T1 - Excretion of oral 9-cis-retinoic acid in the rat. JF - Drug Metabolism and Disposition JO - Drug Metab Dispos SP - 1279 LP - 1281 VL - 24 IS - 11 AU - B Disdier AU - H Bun AU - M Placidi AU - A Durand Y1 - 1996/11/01 UR - http://dmd.aspetjournals.org/content/24/11/1279.abstract N2 - We have studied excretion of oral 9-cis-retinoic acid in urine and feces in vigil rats and in bile in anesthetized rats. A proportion of 53 +/- 13% of the dose of 9-cis-retinoic acid administered was eliminated through the feces in 72 hr, and the urinary excretion was negligible. The prevalent form of elimination in feces and urine was the unchanged compound. Low biliary excretion was, for the most part, composed of metabolites. ER -