@article {Halpert1223, author = {James R. Halpert and Tammy L. Domanski and Orhan Adali and Christine P. Biagini and Jose Cosme and Elizabeth A. Dierks and Eric F. Johnson and Jeffrey P. Jones and Paul Ortiz de Montellano and Richard M. Philpot and Ole Sibbesen and W. Keith Wyatt and Zhoupeng Zheng}, title = {Structure-Function of Cytochromes P450 and Flavin-Containing Monooxygenases}, volume = {26}, number = {12}, pages = {1223--1231}, year = {1998}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {This article is a report on a symposium held at Experimental Biology {\textquoteright}98 in San Francisco, California. Recent developments in site-directed mutagenesis, computer-modeling, and mechanistic analysis of cytochromes P450 and flavin-containing monooxygenases are described. A unifying theme is the elaboration of general approaches for understanding and predicting the function of individual forms of these enzymes. A related goal is the production of soluble forms of mammalian cytochromes P450 for X-ray crystallography. The American Society for Pharmacology and Experimental Therapeutics}, issn = {0090-9556}, URL = {https://dmd.aspetjournals.org/content/26/12/1223}, eprint = {https://dmd.aspetjournals.org/content/26/12/1223.full.pdf}, journal = {Drug Metabolism and Disposition} }