PT - JOURNAL ARTICLE AU - Satoh, Tetsuo AU - Taylor, Palmer AU - Bosron, William F. AU - Sanghani, Sonal P. AU - Hosokawa, Masakiyo AU - Du, Bert N. La TI - Current Progress on Esterases: From Molecular Structure to Function AID - 10.1124/dmd.30.5.488 DP - 2002 May 01 TA - Drug Metabolism and Disposition PG - 488--493 VI - 30 IP - 5 4099 - http://dmd.aspetjournals.org/content/30/5/488.short 4100 - http://dmd.aspetjournals.org/content/30/5/488.full SO - Drug Metab Dispos2002 May 01; 30 AB - This article reports on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the April 2001 Experimental Biology meeting. Current developments in molecular-based studies into the structure and function of cholinesterases, carboxylesterases, and paraoxonases are described. This article covers mechanisms of regulation of gene expression of the various esterases by developmental factors and xenobiotics, as well as the interplay between physiological and chemical regulation of enzyme activity. The American Society for Pharmacology and Experimental Therapeutics