@article {Hinson430, author = {J A Hinson and J R Mitchell}, title = {N-Hydroxylation of phenacetin by hamster liver microsomes.}, volume = {4}, number = {5}, pages = {430--435}, year = {1976}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {Hamster liver microsomes have been shown to catalyze the N-hydroxylation of phenacetin. The reaction, which requires oxygen and NADPH, is inhibited by a carbon monoxide/oxygen atmosphere, indicating that it is catalyzed by a cytochrome P-450-dependent mixed-function oxidase. The N-hydroxyphenacetin can be further metabolized by the microsomes, and the reaction is inhibited by phenacetin.}, issn = {0090-9556}, URL = {https://dmd.aspetjournals.org/content/4/5/430}, eprint = {https://dmd.aspetjournals.org/content/4/5/430.full.pdf}, journal = {Drug Metabolism and Disposition} }