PT  - JOURNAL ARTICLE
AU  - Midha, K K
AU  - Cooper, J K
AU  - Mcgilveray, I J
AU  - Coutts, R T
AU  - Dawe, R
TI  - Metabolism of methoxyphenamine in man and in monkey.
DP  - 1976 Nov 01
TA  - Drug Metabolism and Disposition
PG  - 568--576
VI  - 4
IP  - 6
4099  - http://dmd.aspetjournals.org/content/4/6/568.short
4100  - http://dmd.aspetjournals.org/content/4/6/568.full
SO  - Drug Metab Dispos1976 Nov 01; 4
AB  - Metabolites of methoxyphenamine in the urine of human subjects and monkeys were separated by gas-liquid chromatography and identified by comparison of their chromatographic and mass spectrometric behavior with those of synthetic compounds. Aromatic O-demethylation, aromatic ring hydroxylation (both followed by glucuronide conjugation), and N-demethylation were shown to occur in man as well as in monkey. In man these were the principal metabolites, whereas in the monkey three additional unidentified major metabolites were formed.