TY - JOUR T1 - Identification of 3-O-methyl-alpha-methyldopamine as a urinary metabolite of 3,4-methylenedioxyamphetamine in dog and monkey. JF - Drug Metabolism and Disposition JO - Drug Metab Dispos SP - 143 LP - 148 VL - 5 IS - 2 AU - K K Midha AU - J K Cooper AU - A By AU - J C Ethier Y1 - 1977/03/01 UR - http://dmd.aspetjournals.org/content/5/2/143.abstract N2 - 3-O-Methyl-alpha-methyldopamine has been separated by gas-liquid chromatography (GC) as a metabolite of MDA in the urine of dog and monkey. The metabolite was identified as its mono- and di-trifluoroacetyl derivatives by comparison of their GC and GC-mass spectral properties with those of synthetic compounds. The amount of metabolite increased on hydrolyzing the urine from dosed dogs and monkeys with a preparation containing beta-glucuronidase and sulfatase. ER -