RT Journal Article SR Electronic T1 Characterization of the hepatic microsomal mixed-function oxidase enzyme system in miniature pigs. JF Drug Metabolism and Disposition JO Drug Metab Dispos FD American Society for Pharmacology and Experimental Therapeutics SP 25 OP 27 VO 4 IS 1 A1 R I Freudenthal A1 P Leber A1 D Emmerling A1 G Kerchner A1 D Campbell YR 1976 UL http://dmd.aspetjournals.org/content/4/1/25.abstract AB Hepatic microsomal protein, cytochrome P-450, UDP-glucuronyltransferase, ethylmorphine demethylase, aniline hydroxylase, and aryl hydrocarbon hydroxylase levels were measured in the 2-, 4-, 5-, 6-, and 8-month-old Hanford miniature pig. The activities or concentrations of all of the liver parameters measured had apparently reached their adult plateau level by 2 months of age. The use of the miniature pig in toxicology research programs is discussed.