TY - JOUR T1 - Isolation and identification of the major metabolite of albuterol in human urine. JF - Drug Metabolism and Disposition JO - Drug Metab Dispos SP - 234 LP - 238 VL - 5 IS - 3 AU - C Lin AU - Y Li AU - J McGlotten AU - J B Morton AU - S Symchowicz Y1 - 1977/05/01 UR - http://dmd.aspetjournals.org/content/5/3/234.abstract N2 - The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange chromatography and countercurrent distribution. On the basis of proton magnetic resonance, infrared, and mass-spectral analysis, enzymic hydrolysis, and assay of inorganic sulfate after acid hydrolysis, the metabolite has been identified as the 4'-O-sulfate ester of albuterol. ER -