@article {Breyer-Pfaff114, author = {U Breyer-Pfaff and H Kreft and H Rassner and A Prox}, title = {Formation of sulfone metabolites from chlorpromazine and perazine in man.}, volume = {6}, number = {2}, pages = {114--119}, year = {1978}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {Didesmethylchlorpromazine sulfone [gamma-(2-chlorophenothiazinyl-10)-propylamine sulfone] has been isolated from the urine of a patient under continuous chlorpromazine therapy and identified by mass spectrometry. The same compound was present in organs of rats after injection of the corresponding sulfide. The Cl-free analogue, gamma-(phenothiazinyl-10)-propylamine sulfone, was excreted by patients receiving perazine and by a volunteer after ingestion of the primary amine sulfoxide.}, issn = {0090-9556}, URL = {https://dmd.aspetjournals.org/content/6/2/114}, eprint = {https://dmd.aspetjournals.org/content/6/2/114.full.pdf}, journal = {Drug Metabolism and Disposition} }