PT - JOURNAL ARTICLE AU - J M Frincke AU - G L Henderson TI - The major metabolite of fentanyl in the horse. DP - 1980 Nov 01 TA - Drug Metabolism and Disposition PG - 425--427 VI - 8 IP - 6 4099 - http://dmd.aspetjournals.org/content/8/6/425.short 4100 - http://dmd.aspetjournals.org/content/8/6/425.full SO - Drug Metab Dispos1980 Nov 01; 8 AB - Fentanyl, a potent, synthetic narcotic analgesic, has reportedly been used to "dope" racehorses. Urine was collected from a horse dosed with 70 mg of [3H]fentanyl, and the primary metabolite, a water-soluble, amphoteric compound, was isolated by high-pressure liquid chromatography and identified by spectroscopic analysis. This metabolite was found to be N-[1-(2-phenethyl-4-piperidinyl)] malonanilinic acid.