RT Journal Article
SR Electronic
T1 The major metabolite of fentanyl in the horse.
JF Drug Metabolism and Disposition
JO Drug Metab Dispos
FD American Society for Pharmacology and Experimental Therapeutics
SP 425
OP 427
VO 8
IS 6
A1 J M Frincke
A1 G L Henderson
YR 1980
UL http://dmd.aspetjournals.org/content/8/6/425.abstract
AB Fentanyl, a potent, synthetic narcotic analgesic, has reportedly been used to "dope" racehorses. Urine was collected from a horse dosed with 70 mg of [3H]fentanyl, and the primary metabolite, a water-soluble, amphoteric compound, was isolated by high-pressure liquid chromatography and identified by spectroscopic analysis. This metabolite was found to be N-[1-(2-phenethyl-4-piperidinyl)] malonanilinic acid.