Summary statistics of the physiological parameters in various pathological conditions
Data are median (range).
| Physiological Parameter | Control (n = 61) | Liver-Impaired (n = 8) | Renal-Impaired | ||
|---|---|---|---|---|---|
| Milda (n = 6) | Moderatea (n = 6) | Severea (n = 6) | |||
| CAGP (mg/dl) | 79.5 (54–138) | 43.5 (30–70) | 81 (74–126) | 87.5 (67–132) | 111 (83–166) |
| CAlb (g/dl) | 4.17 (3.6–4.95) | 4.14 (2.53–4.23) | 4.20 (3.7–4.3) | 4.00 (3.8–4.6) | 3.85 (2.9–4.3) |
| Vplasma (liters) (Boer, 1984; Janmahasatian et al., 2005) | 3.43 (2.21–4.4) | 3.51 (2.18–3.74) | 3.4 (2.81–3.67) | 3.52 (3.02–4.12) | 3.27 (3.01–3.98) |
| Vwater (liters) (Watson et al., 1980) | 41.1 (28.4–52.4) | 41.3 (28.1–45) | 39 (32.6–42.4) | 43.2 (36–51.1) | 39.4 (36.5–48) |
| Liver weight (g) (Chouker et al., 2004) | 2070 (1690–2550) | 1990 (1830–2420) | 1800 (1550–2060) | 2240 (1770–2520) | 2100 (1880–2240) |
| GFR (ml/min/1.73 m2) (Levey et al., 1999) | 87.8 (66.1–124) | 78.8 (64.9–85) | 57.4 (37.1–79.5) | 28.7 (21.8–54.8) | 19.5 (11.4–28.6) |
↵a GFR classification based on the Cockcroft-Gault equation: mild (GFR >50 and <80 ml/min), moderate (GFR >30 and <50 ml/min), or severe (GFR <30 ml/min).