Expression level of efflux transporter mRNAs in shRNA-induced knockdown cells
The level in untransduced parental Caco-2 cells was set to 1.0 as the reference. Data are means ± S.D.; n = 3.
| mRNA | VC | P-gp KD | BCRP KD | MRP2 KD |
|---|---|---|---|---|
| P-gp | 0.71 ± 0.34 | 0.20 ± 0.11 | 0.78 ± 0.33 | 0.88 ± 0.17 |
| BCRP | 0.71 ± 0.03 | 0.62 ± 0.15 | 0.14 ± 0.04 | 1.08 ± 0.15 |
| MRP2 | 1.00 ± 0.09 | 1.00 ± 0.09 | 0.63 ± 0.25 | 0.14 ± 0.03 |