Table 3

Correlation (r²) between SV metabolism and CYP activities in human liver microsomes (N = 11)

SV Metabolites	Testosterone 6β-Hydroxylase	Tolbutamide Methylhydroxylase	S-Mephenytoin 4′-Hydroxylase^*	(+)-Bufuralol l′-Hydroxylase	Coumarin 7′-Hydroxylase	Chlorzoxazone 6-Hydroxylase
3′-Hydroxy SV	0.870^**	0.54	0.077	0.14	0.21	0.39
6′-Exomethylene SV	0.874^**	0.57	0.081	0.11	0.21	0.34
3′,5′-Dihydrodiol SV	0.808^**	0.47	0.088	0.09	0.26	0.33
Total metabolism	0.866^**	0.50	0.056	0.13	0.22	0.40