Table 2

Identification of UGT1 RNA transcripts in human liver and biliary epithelial tissues 2-a

LiverBiliary Epithelium
ExpressedNot ExpressedExpressedNot Expressed
UGT1A1UGT1A5 UGT1A1UGT1A5
UGT1A3UGT1A7 UGT1A3UGT1A7
UGT1A4UGT1A8 UGT1A4UGT1A8
UGT1A6UGT1A10 UGT1A6UGT1A92-b
UGT1A92-b  UGT1A10
  • The designation of these transcripts is as recommended at the VIIIth International Workshop on Glucuronidation and the Glucuronosyltransferases, University of Iowa, May 19–22, 1996. Oligonucleotide primers used for the analysis of the UGT1 transcripts were based upon the DNA sequences deposited in GenBank.

  • 2-a Analysis of transcripts conducted by reverse transcriptase-polymerase chain reaction using human tissue RNA was conducted as outlined in ref. 45.

  • 2-b The designation of UGT1A9 has been identified previously as HlugP4 (40).