Table 3

Immunoinhibition of lauric acid hydroxylation

Antibody% of Total Radioactivity3-a
Hydroxylauric AcidLauric acid
11-OH (ω-1)10-OH (ω-2)6-OH (ω)
Preimmune IgG3-b 15.3 ± 3.83.0 ± 0.72.6 ± 0.977.1 ± 3.2
(100)3-c (100)(100)(100)
LMC1 IgG14.7 ± 3.23.0 ± 1.10.1 ± 0.280.9 ± 4.1
 (96) (100)(3.9)(105)
LMC2 IgG8.1 ± 1.51.1 ± 0.94.6 ± 0.185.1 ± 2.6
 (53)  (37)(177)(110)

  • ↵3-a Mean ± S.D. of three replicates using microsomes from juvenile male trout.

  • ↵3-b Incubations without added IgG gave values of 12.3 ± 1.9 (11-OH), 2.2 ± 1.3 (10-OH), 3.1 ± 0.8 (6-OH), and 80.7 ± 2.4 (lauric acid), respectively.

  • ↵3-c Numbers in parentheses are % of control (preimmune IgG).