Table 3

Quantitative estimation of metabolites (% of dose) of¹⁴C-CP-93,393 in urine and bile of LE rat

Metabolite	Urine		Bile		Total
Metabolite	Male	Female	Male	Female	Male	Female
M1	1.20	0.84	8.52	4.29	9.72	5.13
M2	0.33	0.52	2.39	1.08	2.73	1.60
M3	—	—	0.83	0.13	0.83	0.13
M4	1.68	0.50	0.65	0.42	2.33	0.92
M5	—	—	1.05	0.36	1.05	0.36
M6	0.37	0.25	—	—	0.37	0.25
M7	1.31	1.62	24.65	21.21	25.97	22.83
M8+M9	1.48	1.54	2.20	1.20	3.68	2.74
M10	0.30	1.16	0.71	0.56	1.01	1.72
M11	0.47	0.57	1.71	0.46	2.18	1.03
M12	0.73	0.52	7.50	6.22	8.23	6.74
M13	0.66	0.46	20.99	7.41	21.66	7.87
M14	0.10	0.16	1.12	0.29	1.21	0.45
M15	5.67	2.71	0.62	5.79	6.28	8.50
M16	0.40	0.36	0.12	0.61	0.52	0.97
M17	1.25	19.19	0.33	2.25	1.58	21.44
Total	15.93	30.40	73.39	52.27	89.33	82.67