Percentages of metabolites of CP-93,393 in urine, bile, and feces of monkeys after oral administration of 14C-CP-93,393 at a dose of 5 mg/kg.
| Metabolite | Retention Time (min:sec) | % of Recovered Radioactivity | ||
|---|---|---|---|---|
| Urine | Bile | Feces | ||
| M19 | 6:20 | 2.18 | 3.19 | — |
| M20 | 8:52 | 11.01 | 1.28 | 2.36 |
| M21 | 9:29 | 3.38 | — | 1.65 |
| M22 | 10:11 | 1.95 | 3.61 | 0.91 |
| M23 | 11:38 | 1.57 | — | 5.24 |
| M6 | 13:37 | 2.57 | 0.90 | 6.00 |
| M18 | 16:18 | 5.64 | 48.24 | 14.45 |
| M7 | 16:50 | 11.42 | 1.65 | — |
| M9 | 18:01 | 2.61 | 3.09 | 3.09 |
| M8 | 18:48 | 1.38 | — | — |
| M11 | 19:29 | 2.58 | — | 1.47 |
| M24 | 20:52 | 2.89 | 1.18 | 6.23 |
| M13 | 22:28 | 31.04 | 28.79 | 10.85 |
| M25 | 23:33 | 1.19 | 2.72 | 0.35 |
| M15 | 24:04 | 5.23 | 1.35 | 37.40 |
| M26 | 25:22 | — | — | 1.68 |
| Parent drug | 27:42 | 3.49 | 0.64 | 0.64 |
| 90.11 | 93.45 | 92.32 | ||
* Average of male and female monkeys.