Mean (±SD) apparent aldo-keto reductase kinetic constants for DA-125 in the liver of SHRs, Kyoto-Wistar rats, DOCA-salt rats, and Sprague-Dawley rats at 16 weeks old
| Rats | Vmax | KM |
|---|---|---|
| 10−9 mol/min/mg protein | mM | |
| SHRs | 7.42 ± 0.802 | 0.221 ± 0.0351 |
| Kyoto-Wistar rats | 7.48 ± 1.42 | 0.224 ± 0.0704 |
| DOCA-salt rats | 3.05 ± 0.238 | 0.0995 ± 0.0194 |
| Sprague-Dawley rats | 3.39 ± 0.653 | 0.113 ± 0.0514 |
There was no significant (p < 0.05) difference between SHRs and Kyoto-Wistar rats, and between DOCA-salt rats and Sprague-Dawley rats, respectively.