HPLC analysis of bile after oral administration of a single dose of [14C]D2916 at 20 mg/kg to male and female rats
| Time after Administration | Males | Females | ||
|---|---|---|---|---|
| D3269 | D3389 + Unknown Metabolites | D3269 | D3389 + Unknown Metabolites | |
| hr | ||||
| 0–6 | 21.8 | 70.7 | 75.6 | 19.5 |
| 6–24 | 17.4 | 72.8 | 80.7 | 15.6 |
Results, given in percentage of biliary radioactivity, are obtained from a pool of five rats.