Sham (N = 8) | MI (N= 9) | |
---|---|---|
Clearance (ml/min) | 1.12 ± 0.17 | 0.86 ± 0.20* |
t 1/2β (min) | 96 ± 16 | 141 ± 49* |
Vdss (ml) | 137 ± 15 | 151 ± 20 |
Values are means ± SD. t1/2β, terminal elimination half-life; Vdss , volume of distribution at steady-state.
p value is as follows: *significantly different from the values of the sham group, p < 0.05.