Table 2

Metabolism of [¹⁴C] cerivastatin by human liver microsomes ^2-a

Microsomal Batch No.	Incubation Time (min)	Individual Metabolites as Percentage of Total Metabolites^2-b
Microsomal Batch No.	Incubation Time (min)	Cerivastatin	M-1	M-23	M-24	Unknown 1
1	20	95.6	2.4	2.1	—^2-c	—^2-c
	60	80.2	11.2	8.1	— ^2-c	0.9
2	20	91.1	6.8	2.1	— ^2-c	—^2-c
	60	72.3	19.7	7.5	— ^2-c	—^2-c
3	20	90.0	6.0	4.1	— ^2-c	—^2-c
	60	82.7	10.2	7.3	— ^2-c	—^2-c
4	20	66.0	15.7	17.0	— ^2-c	1.4
	60	34.3	27.1	29.1	7.8	1.1