Table 1

Mean excreted amounts of NMP, 5-HNMP, MSI, and 2-HMSI in urine from three healthy volunteers for 6 days

DayExcreted Amount of Metabolite
NMP5-HNMPMSI2-HMSI
mg mg mg mg
10.850.00.4310.2
2ND1-a 1.00.0510.1
3NDND0.013.6
4NDNDND1.1
5NDNDND0.5
6NDNDND0.2

An oral dose of 100 mg NMP was given at the beginning of day 1

  • 1-a ND, not detected (concentration was below the detection limit).