Excretion of total radioactivity
| Dose | N | Urine1-a | 0–24 Hr Feces | Total | Urine1-a | 0–96 Hr Feces | Total |
|---|---|---|---|---|---|---|---|
| μg/kg | |||||||
| 3 | 3 | 6.3 ± 2.7 | 17.3 ± 1.4 | 23.4 ± 3.2 | 11.2 ± 3.5 | 38.1 ± 0.5 | 49.4 ± 3.9 |
| 25 | 4 | 23.9 ± 7.8 | 59.2 ± 9.6 | 83.1 ± 15.8 | 26.4 ± 7.9 | 75.8 ± 9.0 | 102.2 ± 13.4 |
| 250 | 4 | 24.8 ± 6.5 | 64.2 ± 7.8 | 89.1 ± 11.0 | 25.8 ± 5.2 | 78.4 ± 6.5 | 103.7 ± 8.2 |
Results are means ± SD (% of dose) obtained after intravenous administration of [3H]l-738,167 to dogs.
↵1-a Including cage wash.