Metabolites | Amounts of selegiline · HCl administered | Time (hr) | ||
---|---|---|---|---|
0–24 | 24–48 | 48–72 | ||
Selegiline | 10 | 0.22 | —2-a | ND2-b |
5 | 0.22 | — | — | |
2.5 | — | — | — | |
Amphetamine | 10 | 2.54 | 1.08 | ND |
5 | 1.72 | 1.32 | 0.28 | |
2.5 | 2.01 | 0.42 | 0.15 | |
Methamphetamine | 10 | 33.77 | 10.31 | ND |
5 | 32.13 | 10.22 | 1.87 | |
2.5 | 32.54 | 5.33 | 1.34 | |
Desmethylselegiline | 10 | 0.94 | 0.03 | ND |
5 | 0.76 | 0.06 | — | |
2.5 | 1.17 | 0.12 | — | |
Norpseudoephedrine | 10 | 0.03 | — | ND |
5 | 0.01 | — | — | |
2.5 | 0.02 | — | — | |
Norephedrine | 10 | 0.08 | 0.01 | ND |
5 | 0.12 | — | — | |
2.5 | 0.12 | — | — | |
Ephedrine | 10 | 0.62 | 0.04 | ND |
5 | 0.44 | 0.03 | 0.01 | |
2.5 | 0.41 | 0.03 | — | |
Pseudoephedrine | 10 | 0.04 | — | ND |
5 | 0.03 | — | — | |
2.5 | 0.02 | — | — | |
p-Hydroxyamphetamine | 10 | 1.92 | 0.79 | ND |
5 | 1.84 | 0.84 | 0.66 | |
2.5 | 2.04 | 1.12 | 0.84 | |
p-Hydroxymethamphetamine | 10 | 4.47 | 1.49 | ND |
5 | 4.86 | 1.16 | 0.37 | |
2.5 | 3.61 | 1.10 | 0.35 |