Table 2

Urinary recovery (%) of metabolites of selegiline according to various doses

MetabolitesAmounts of selegiline · HCl administeredTime (hr)
0–2424–4848–72
Selegiline100.222-a ND2-b
50.22
2.5
Amphetamine102.541.08ND
51.721.320.28
2.52.010.420.15
Methamphetamine1033.7710.31ND
532.1310.221.87
2.532.545.331.34
Desmethylselegiline100.940.03ND
50.760.06
2.51.170.12
Norpseudoephedrine100.03ND
50.01
2.50.02
Norephedrine100.080.01ND
50.12
2.50.12
Ephedrine100.620.04ND
50.440.030.01
2.50.410.03
Pseudoephedrine100.04ND
50.03
2.50.02
p-Hydroxyamphetamine101.920.79ND
51.840.840.66
2.52.041.120.84
p-Hydroxymethamphetamine104.471.49ND
54.861.160.37
2.53.611.100.35
  • 2-a —, below detection limit.

  • 2-b ND, not detected.