Table 2

Effect of dose on pharmacokinetics of ¹³¹I-LEX 032: organ/blood ratio (based on the mean of % ad. dose values from six rats)

Tissue	Time
	5 Min		1 Hr		2 Hr
	Carrier-free^2-a	15 mg/kg	30 mg/kg	Carrier-free^2-a	15 mg/kg	30 mg/kg	Carrier-free^2-a	15 mg/kg	30 mg/kg
Blood	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
Intestine	0.09	0.09	0.12	0.77	1.37	0.84	1.25	0.79	0.51
Heart	0.16	0.17	0.22	0.29	0.34	0.21	0.25	0.29	0.33
Lungs	0.78	0.41	0.38	1.03	0.79	0.51	0.88	1.07	0.56
Muscle	0.03	0.05	0.03	0.17	0.14	0.18	0.13	0.14	0.14
Spleen	0.69	0.56	0.34	2.00	1.69	1.22	1.25	1.64	0.65
Kidneys	3.83	3.14	3.62	9.82	22.96	9.30	4.75	18.64	10.48
Liver	1.96	1.72	0.46	2.31	0.45	1.13	1.25	2.00	0.84
Thyroid	0.94	1.36	0.86	10.39	70.37	96.50	177.30	319.90	828.14
Prostrate	0.07	0.07	0.06	1.31	0.45	0.59	0.56	0.50	1.00
Skin	0.04	0.03	0.04	0.41	0.35	0.57	0.50	0.50	1.93

↵2-a Approximately 0.24 mg/kg.