Table 1

Correlation among the activities of S-oxidases involved in the metabolism of flosequinan by liver microsomes from untreated male and female rats and rats treated with inducers

Pathways	Correlation between DifferentS-Oxidation Pathways		Correlation between Different Substrate Concentrations
	50 μM^a			1 mM^b
	FS ↓ S-FSO	R-FSO ↓ FSO₂		S-FSO ↓ FSO₂	FS ↓ S-FSO	R-FSO ↓ FSO₂	S-FSO ↓ FSO₂
	[correlation coefficient (r)]
FS →R-FSO	0.67	0.51	0.44	0.97	0.90	0.87	0.45
FS→S-FSO		0.82	0.66		0.91	0.83	0.53
R-FSO → FSO₂			0.92			0.92	0.82
S-FSO→ FSO₂			—			—	0.87

^{a, b} Substrate concentration.