Time (hr postdose) | Urine | Feces | Total | |||
---|---|---|---|---|---|---|
3H | 14C | 3H | 14C | 3H | 14C | |
0–4 | 0.89 ± 0.45 | 0.97 ± 0.49 | — | — | 0.90 ± 0.45 | 0.97 ± 0.49 |
4–12 | 8.31 ± 1.69 | 9.09 ± 1.81 | — | — | 8.32 ± 1.69 | 9.09 ± 1.80 |
12–24 | 4.00 ± 0.82 | 3.81 ± 0.87 | 15.14 ± 5.24 | 14.08 ± 4.62 | 19.15 ± 5.34 | 17.90 ± 4.60 |
24–48 | 2.67 ± 0.59 | 2.11 ± 0.55 | 28.65 ± 3.77 | 27.29 ± 4.00 | 31.32 ± 3.61 | 29.40 ± 3.78 |
48–72 | 1.16 ± 0.40 | 0.96 ± 0.30 | 8.47 ± 1.47 | 8.09 ± 1.28 | 9.63 ± 1.60 | 9.04 ± 1.35 |
72–96 | 0.72 ± 0.19 | 0.64 ± 0.16 | 4.97 ± 2.93 | 4.74 ± 2.82 | 5.70 ± 2.88 | 5.39 ± 2.80 |
96–120 | 0.60 ± 0.07 | 0.55 ± 0.07 | 2.75 ± 0.07 | 2.66 ± 0.08 | 3.35 ± 0.08 | 3.21 ± 0.08 |
120–144 | 0.51 ± 0.14 | 0.45 ± 0.11 | 2.25 ± 0.73 | 2.11 ± 0.69 | 2.75 ± 0.64 | 2.55 ± 0.62 |
144–168 | 0.57 ± 0.17 | 0.50 ± 0.13 | 1.67 ± 0.45 | 1.63 ± 0.42 | 2.24 ± 0.61 | 2.13 ± 0.55 |
168–264 | 1.15 ± 0.17 | 0.99 ± 0.17 | 4.20 ± 0.45 | 3.93 ± 0.80 | 5.35 ± 0.93 | 4.92 ± 0.85 |
Total | 20.59 ± 0.96 | 20.07 ± 1.12 | 68.11 ± 4.77 | 64.52 ± 4.96 | 88.69 ± 4.72 | 84.59 ± 5.05 |
Percentage of 3H and 14C excreted in urine and feces from 0 to 264 hr