Treatment | Tissue | Cytochrome P450 | UROX | EROD |
---|---|---|---|---|
nmol/mg protein | pmol product/min/mg protein | |||
None | Liver | 0.16 ± 0 | 4 ± 0.3 | 20 ± 0 |
Kidney | 0.15 ± 0 | <1.5 | 0 | |
3-MC | Liver | 0.69 ± 0.03 | 192 ± 8 | 4080 ± 100 |
Kidney | 0.22 ± 0 | 25 ± 2 | 195 ± 15 |
↵2-a 12-day-old chickens were treated with 3-methylcholanthrene (MC) and microsomes prepared as described inMethods. Uroporphyrinogen oxidation was determined in the presence of 7 μM TCB. Values represent means and ranges of duplicate determinations.