Tissue pharmacokinetic parameters of tea polyphenols after i.v. administration of DGT (25 mg/kg) to rats
| Tissue | EGCG | EGC | EC | |||
|---|---|---|---|---|---|---|
| t1/2 | AUC | t1/2 | AUC | t1/2 | AUC | |
| min | μg × min/g | min | μg × min/g | min | μg × min/g | |
| Liver | 138.6 | 104.8 | 49.5 | 85.6 | 31.5 | 26.3 |
| Kidney | 38.5 | 325.5 | 28.9 | 1,427.4 | 27.7 | 335.7 |
| Lung | 99.0 | 410.6 | 43.3 | 1,209.7 | 49.5 | 87.0 |
| Intestine | 173.3 | 1,707.9 | 40.8 | 868.4 | 46.2 | 373.4 |
Values were calculated from the data points shown in fig.5.