Pharmacokinetic parameters of FK143 after intravenous administration to rats
| Dose | CLtot | MRT | VdSS | t1/2 |
|---|---|---|---|---|
| mg/kg | ml/min/kg | hr | liters/kg | hr |
| 1 | 6.96 | 9.84 | 4.11 | 10.31 |
| ±0.02 | ±2.60 | ±1.10 | ±2.41 | |
| 5 | 8.76 | 6.34 | 3.33 | 9.83 |
| ±0.83 | ±0.36 | ±0.50 | ±1.90 |
Optimal estimated values ± SE (N = 3).