Relative abundance of radiometric HPLC peaks A–J 1-a
| Treatment | % 14C-CBZ Dose1-b | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| A | B | C | D | E | F | G | H | I | J | |
| CBZ | 0.9 | 6.8 | 1.0 | 0.4 | 0.9 | 0.4 | 3.2 | 4.6 | 1.6 | 2.9 |
| CBZ/PB | 1.2 | 6.1 | 1.5 | 1.7 | 1.4 | 0.8 | 3.0 | 7.9 | 1.3 | 2.2 |
| CBZ/STP | 0.7 | 15.6 | 3.7 | 0.4 | 0.9 | 0.7 | 2.1 | 8.9 | 1.5 | 4.2 |
| % Recovered Urinary Radioactivity1-c | ||||||||||
| A | B | C | D | E | F | G | H | I | J | |
| CBZ | 2.8 | 21.4 | 3.1 | 1.1 | 2.9 | 1.2 | 10.2 | 14.6 | 4.9 | 9.2 |
| CBZ/PB | 3.2 | 16.4 | 4.0 | 4.5 | 3.7 | 2.1 | 8.1 | 21.4 | 3.6 | 5.9 |
| CBZ/STP | 1.4 | 30.7 | 7.3 | 0.9 | 1.7 | 1.3 | 4.2 | 17.5 | 2.9 | 8.3 |
↵1-a Peak description as indicated in radiochromatogram (fig. 2b).
↵1-b Integrated 14C peak areas (cpm) expressed as a percentage of total 14C-CBZ dose. Percentages reflect the fraction of total radioactivity dosed that was recovered in urine as an individual metabolite.
↵1-c Integrated 14C peak areas (cpm) expressed as a percentage of total radioactivity recovered in urine. Percentages reflect the fraction of total radioactivity injected onto the column that is accounted for by an individual metabolite.