Table 4

Tissue distribution of 2,4-D derived radioactivity in rats (200 mg/kg) nmoles/gram of tissue

Males	2 Hr	8 Hr	24 Hr	72 Hr
Blood	1026 ± 306	1501 ± 172	97 ± 42^*	12 ± 7
Liver	608 ± 190	891 ± 101	48 ± 34^*	7 ± 3
Kidney	659 ± 108	870 ± 89	247 ± 150	21 ± 2
Muscle	171 ± 69	226 ± 20	14 ± 7^*	15 ± 4
Skin	293 ± 78	526 ± 89	57 ± 28^*	39 ± 23
Fat	126 ± 40	174 ± 21	78 ± 19	73 ± 16
Testes	205 ± 66	293 ± 28	19 ± 12	4 ± 2
Brain	74 ± 34	99 ± 13	5 ± 4^*	3 ± 2
Females
Blood	1371 ± 154	1248 ± 143	861 ± 118	3 ± 1
Liver	885 ± 127	839 ± 132	323 ± 27	3 ± 1
Kidney	951 ± 95	941 ± 101	584 ± 49	22 ± 4
Muscle	314 ± 46	319 ± 49	129 ± 12	6 ± 4
Skin	463 ± 50	462 ± 60	270 ± 21	43 ± 10
Fat	204 ± 35	229 ± 29	113 ± 7	64 ± 16
Ovaries	554 ± 85	594 ± 99	357 ± 52	22 ± 7
Brain	169 ± 36	151 ± 31	40 ± 2	<1

* Significantly different from female results at that time point by a Student’s t-test or a Mann-Whitney test (p ≤ 0.05).
N = 4 at 2 and 8 hr and N = 3 at 24 and 72 hr.