Table 3

Effects of treatment with bezafibrate or fenofibrate on the activities of enzymes involved in benzoylglycine formation in solubilized mitochondria isolated from rat liver

Treatment^3-a	Enzymatic Activity
Treatment^3-a	Benzoyl-CoA Synthetase	Benzoyl-CoA Hydrolase	Benzoyl-CoA/Glycine N-Acyltransferase
	nmol/min · mg of protein
None	6.91 ± 1.9	1.41 ± 0.2	72.1 ± 5.5
Bezafibrate	6.39 ± 0.9	2.32 ± 0.3^3-b	56.7 ± 2.8^3-b
Fenofibrate	7.94 ± 1.2	2.49 ± 0.1^3-b	58.3 ± 3.1^3-b

Values are the mean ± SE for five to eight rats.
↵3-a Rats were fed ground chow or ground chow containing bezafibrate or fenofibrate (2.5 mmol/kg of feed) for 10 days.
↵3-b Significantly different (p < 0.05) from rats not fed fibrate.