Table 7

Excretion of radioactivity in bile, urine and feces of baboons dosed with [3H]L-732,531

% Dose
IV (0.2 mg/kg)PO (1 mg/kg)PO (5 mg/kg)
Intact Baboons
 Feces75.6  ± 25.480.4  ± 25
 Urine1.1  ± 0.312.5  ± 20.7
Cannulated Baboons
 Bile9.2  ± 3.4
 Feces76  ± 21
 Urine0.14  ± 0.02
  • Data represent mean ± SD, N = 3.