Summary of NMR data for carvedilol and metabolites
| Compound | Chemical Shifts of Aromatic Protons | |||||||
|---|---|---|---|---|---|---|---|---|
| H1 | H2 | H3 | H5 | H6 | H7 | H8 | Catechol | |
| ppm | ||||||||
| Carvedilol2-a | 7.06 | 7.26 | 6.66 | 8.28 | 7.09 | 7.30 | 7.39 | 6.89, 6.84 |
| M8 2-b | 6.98, 6.89 | |||||||
| M17 2-b | 7.19 | 7.28 | 6.67 | 7.93 | 6.98 | 7.09 | 6.97, 6.88 | |
| M15 2-b | 7.07 | 6.55 | 8.19 | 7.07 | 7.30 | 7.60 | 6.92, 6.84 | |
| M21 2-b | 7.09 | 6.90 | 8.22 | 7.11 | 7.32 | 7.62 | 6.90, 6.81 | |
| M1a 2-b | 7.07 | 7.28 | 6.70 | 8.17 | 7.08 | 7.30 | 7.42 | 6.92, 6.83 |
| M23 2-b | 7.06 | 7.30 | 6.68 | 8.22 | 7.07 | 7.30 | 7.40 | 6.94, 6.84 |