Table 2

Uptake of benzylpenicillin and glycylsarcosine by freshly isolated brain capillary endothelial cells

TracerConditionTracer/Sucrose RatioNp Value2-a
% of control
[3H]Benzylpenicillin pH 6.51002-b 5
 Ceftibuten (0.66 μM), pH 6.5139.6  ± 5.45NS
[14C]Glycylsarcosine pH 6.51002-b 5
 Ceftibuten (0.66 μM), pH 6.597.9  ± 1.65NS
  • Values are means ± SE of N experiments.

  • 2-a By two-tailed Student’s t test. NS, statistically not significant (p > 0.05, adjusted by Bonferroni’s correction for multiple comparisons).

  • 2-b Control value, which was defined as 100%.