Rates of 7-EC biotransformation by rat and bovine liver slices (mean of three animals for each species), as measured by radio-HPLC analysis
| 7-OHC Glucuronide | 7-OHC Sulfate | 7-OHC | 7-EC | |
|---|---|---|---|---|
| Rat (pmol metabolite/min/mg protein) | 7.9 ± 1.8 | 29.7 ± 4.0 | 4.4 ± 0.9 | 72.1 ± 7.2 |
| Bovine (pmol metabolite/min/mg protein) | 0.1 ± 0.0 | 0.3 ± 0.1 | 5.7 ± 0.9 | 107.2 ± 12.1 |
| Retention time (min) | 3.6 | 5.8 | 17.0 | 31.0 |