Table 4

Fractional rate constants for uptake (k in) and excretion (k out) of 21 μM taurocholic acid in human hepatocytes

Tissue Sourcekinkout
10−3/min 10−3/min
Tx-livers4-a 2.8  ± 0.5 (19)62.3  ± 10.2 (19)
PH-livers3.8  ± 0.4 (11)52.8  ± 4.7 (9)

Results are expressed as mean ± SE (N).

  • 4-a Obtained from donors older than 15 years of age.