Experimental design: A, iv rac-CPF administration in dogs with nondiverted bile flow; B, iv rac-CPF administration in dogs with diverted bile flow; C, id administration of bile containing (R,S)-Gluc in dogs with nondiverted bile flow; D, iv administration of bile containing (R,S)-Gluc in dogs with nondiverted bile flow
| Phase of administration | Dogs | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | |
| I | B | B | A | A | A | A | A | A | A |
| II | A | A | C | C | C | C | C | C | C |
| III | C | C | B | B | B | B | B | B | B |
| IV | D | D | D | D | D | D | D | D | D |