Drug | IC50 (μM) |
---|---|
Chloroquine | >500 |
Halofantrine | 19 |
Mefloquine | 92 |
Quinine | >500 |
Quinidine | 235 |
↵3-a Arteether (100 μM) was incubated with increasing concentrations of each antimalarial drug. DQHS production was measured in human liver donors 7 and 18, and the IC50 values were calculated as described in Materials and Methods.