Table 2

Summary of fitted parameters from the DM (set A, DM without t₀; set B, DM with GM t₀; set C, DM with fitted t₀) and the GM

Solute	Parameter		Goodness of Fit Criteria
Solute	D_N	V_B		t₀	k₁₂	k₂₁	k_e	CD	MSC
		ml	% liver weight	sec	sec⁻¹	sec⁻¹	sec⁻¹
BSPGSH (13 ± 2 g liver)
GM	NA^2-a	2.7 ± 0.8	21 ± 6	4.1 ± 1.1	0.08 ± 0.05	0.005 ± 0.004	0.029 ± 0.012	NA	NA
DM set A	0.04 ± 0.01	3.0 ± 0.8^2-b	23 ± 7^2-b	0	0.08 ± 0.03	0.033 ± 0.017^2-b	0.055 ± 0.009^2-b	0.98 ± 0.01	4.05 ± 0.73
DM set B	0.19 ± 0.09^2-c	3.0 ± 0.9^2-b	23 ± 7^2-b	4.1 ± 1.1	0.08 ± 0.05	0.013 ± 0.008^b,c	0.041 ± 0.010^b,c	NA	NA
DM set C	0.16 ± 0.08^2-d	3.0 ± 0.9^2-b	23 ± 7^2-b	3.6 ± 1.2	0.08 ± 0.04	0.013 ± 0.007^b,d	0.041 ± 0.008^b,d	0.99 ± 0.01^2-d	4.86 ± 0.85^2-d
HA (11 ± 1.3 g liver)
GM	NA	3.0 ± 0.5	27 ± 4	4.3 ± 1.1	0.063 ± 0.023	0.091 ± 0.026	0	NA	NA
DM set A	0.08 ± 0.05	2.9 ± 0.5	26 ± 5	0	0.069 ± 0.024	0.073 ± 0.016^2-b	0	0.98 ± 0.01	3.97 ± 0.62
DM set B	0.43 ± 0.16^2-c	3.4 ± 0.7^b,c	30 ± 5^b,c	4.3 ± 1.1	0.066 ± 0.069	0.107 ± 0.048^2-c	0	NA	NA
DM set C	0.18 ± 0.09^2-d	3.0 ± 0.5	27 ± 4	2.2 ± 1.2^2-b	0.056 ± 0.018^b,d	0.073 ± 0.022^2-b	0	0.99 ± 0.01^2-d	4.44 ± 0.86^2-d

↵2-a NA, not applicable.
↵2-b Significantly different from data from the GM (p < 0.05, paired t test).
↵2-c Set B significantly different from set A (p < 0.05, paired t test).
↵2-d Set C significantly different from set A (p < 0.05, paired t test).