P450 content and monooxygenase activities in liver microsomes from untreated male and female cynomolgus monkeys
| Parameters | Male (N = 13) | Female (N = 12) |
|---|---|---|
| P450 content (nmol/mg of protein) | 0.62 ± 0.12 | 0.66 ± 0.10 |
| AnH (nmol/min/mg of protein) | 0.51 ± 0.15 | 0.42 ± 0.18 |
| CLZ6H (nmol/min/mg of protein) | 3.5 ± 2.1 | 3.9 ± 1.1 |
| DMNd (nmol/min/mg of protein) | 0.25 ± 0.16 | 0.36 ± 0.24 |
| pNPH (nmol/min/mg of protein) | 0.56 ± 0.27 | 0.67 ± 0.21 |
Data are presented as mean ± SD from experiments performed at least in duplicate, using microsomes prepared from single animals.